CAS 85622-95-3|Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide,3-(2-chloroethyl)-3,4-dihydro-4-oxo-

Introduction：Basic information about CAS 85622-95-3|Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide,3-(2-chloroethyl)-3,4-dihydro-4-oxo-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Synonyms

Common Name	Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide,3-(2-chloroethyl)-3,4-dihydro-4-oxo-
CAS Number	85622-95-3	Molecular Weight	242.62200
Density	1.94g/cm3	Boiling Point	555.8ºC at 760 mmHg
Molecular Formula	C₇H₇ClN₆O₂	Melting Point	/
MSDS	/	Flash Point	289.9ºC

Names

Name	3-(2-chloroethyl)-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.94g/cm3
Boiling Point	555.8ºC at 760 mmHg
Molecular Formula	C₇H₇ClN₆O₂
Molecular Weight	242.62200
Flash Point	289.9ºC
Exact Mass	242.03200
PSA	108.17000
Index of Refraction	1.834
InChIKey	QXYYYPFGTSJXNS-UHFFFAOYSA-N
SMILES	NC(=O)c1ncn2c(=O)n(CCCl)nnc12

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NJ5927000

CHEMICAL NAME :: Imidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxamide, 3-(2-chloroethyl)-3,4-dihydro-4-oxo-

CAS REGISTRY NUMBER :: 85622-95-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C7-H7-Cl-N6-O2

MOLECULAR WEIGHT :: 242.65

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human

DOSE/DURATION :: 3108 ug/kg

TOXIC EFFECTS :: Gastrointestinal - nausea or vomiting Blood - changes in bone marrow (not otherwise specified)

TYPE OF TEST :: LD10 - Lethal Dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 45 mg/kg

TOXIC EFFECTS :: Blood - changes in cell count (unspecified) Blood - changes in bone marrow (not otherwise specified) Tumorigenic - active as anti-cancer agent

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 40 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Rodent - mouse Leukocyte

DOSE/DURATION :: 50 umol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 44,1767,1984

Synonyms

Azolastone

Mitozolamide

Mitozolomide

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