CAS 1238-43-3|Hydroxyevodiamine

Introduction：Basic information about CAS 1238-43-3|Hydroxyevodiamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Hydroxyevodiamine BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Hydroxyevodiamine
CAS Number	1238-43-3	Molecular Weight	319.357
Density	1.5±0.1 g/cm3	Boiling Point	633.4±55.0 °C at 760 mmHg
Molecular Formula	C₁₉H₁₇N₃O₂	Melting Point	190 °C
MSDS	/	Flash Point	336.9±31.5 °C

Names

Name	Hydroxyevodiamine
Synonym	More Synonyms

Hydroxyevodiamine BiologicalActivity

Description	Hydroxyevodiamine (Rhetsinine) inhibits aldose reductase with an IC50 value of 24.1 μM[1].
Related Catalog	Signaling Pathways >>Metabolic Enzyme/Protease >>Aldose ReductaseResearch Areas >>Inflammation/Immunology
References	[1]. A Kato, et al. Inhibitory effect of rhetsinine isolated from Evodia rutaecarpa on aldose reductase activity. Phytomedicine. 2009 Mar;16(2-3):258-61.

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	633.4±55.0 °C at 760 mmHg
Melting Point	190 °C
Molecular Formula	C₁₉H₁₇N₃O₂
Molecular Weight	319.357
Flash Point	336.9±31.5 °C
Exact Mass	319.132080
PSA	59.57000
LogP	0.46
Vapour Pressure	0.0±1.9 mmHg at 25°C
Index of Refraction	1.797
InChIKey	XYSMNZWLVJYABK-UHFFFAOYSA-N
SMILES	CN1c2ccccc2C(=O)N2CCc3c([nH]c4ccc(O)cc34)C21
Storage condition	2-8°C

Synonyms

(13bS)-10-Hydroxy-14-methyl-8,13,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one

Hydroxy-evodiamin

Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one, 8,13,13b,14-tetrahydro-13b-hydroxy-14-methyl-

Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one, 8,13,13b,14-tetrahydro-10-hydroxy-14-methyl-, (13bS)-

13b-Hydroxy-14-methyl-8,13,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one

Recommended......