Introduction：Basic information about CAS 1407-03-0|Ammonium Glycyrrhizinate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ammonium Glycyrrhizinate |
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| CAS Number | 1407-03-0 | Molecular Weight | 839.96300 |
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| Density | / | Boiling Point | 971.4ºC at 760 mmHg |
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| Molecular Formula | C42H65NO16 | Melting Point | / |
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| MSDS | Chinese | Flash Point | 288.1ºC |
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Names
| Name | glycyrrhizic acid ammonium salt |
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| Synonym | More Synonyms |
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Ammonium Glycyrrhizinate BiologicalActivity
| Description | Ammonium glycyrrhizinate is a triterpenoid saponin, acting as a direct HMGB1 antagonist, with anti-inflammatory， anti-tumor, anti-diabetic activities[1][2][3]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| Target | HMGB1[1] |
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| References | [1]. Li C, et al. Glycyrrhizin, a Direct HMGB1 Antagonist, Ameliorates Inflammatory Infiltration in a Model of Autoimmune Thyroiditis via Inhibition of TLR2-HMGB1 Signaling. Thyroid. 2017 May;27(5):722-731. [2]. Su X, et al. Glycyrrhizic acid: A promising carrier material for anticancer therapy. Biomed Pharmacother. 2017 Nov;95:670-678. |
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Chemical & Physical Properties
| Boiling Point | 971.4ºC at 760 mmHg |
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| Molecular Formula | C42H65NO16 |
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| Molecular Weight | 839.96300 |
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| Flash Point | 288.1ºC |
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| Exact Mass | 839.43000 |
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| PSA | 270.28000 |
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| LogP | 2.56950 |
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| Vapour Pressure | 0mmHg at 25°C |
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| InChIKey | ILRKKHJEINIICQ-AACVESJGSA-N |
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| SMILES | CC1(C(=O)O)CCC2(C)CCC3(C)C(=CC(=O)C4C5(C)CCC(OC6OC(C(=O)O)C(O)C(O)C6OC6OC(C(=O)O)C(O)C(O)C6O)C(C)(C)C5CCC43C)C2C1.N |
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| Storage condition | 2-8°C |
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Safety Information
| WGK Germany | 2 |
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| RTECS | LZ6500000 |
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Synonyms
