CAS 142203-65-4|9-Dihydro-13-acetylbaccatin III

Introduction：Basic information about CAS 142203-65-4|9-Dihydro-13-acetylbaccatin III, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 9-Dihydro-13-acetylbaccatin III BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	9-Dihydro-13-acetylbaccatin III
CAS Number	142203-65-4	Molecular Weight	630.68
Density	1.3±0.1 g/cm3	Boiling Point	601.4±55.0 °C at 760 mmHg
Molecular Formula	C₃₃H₄₂O₁₂	Melting Point	/
MSDS	/	Flash Point	193.0±25.0 °C

Names

Name	13-Acetyl-9-dihydrobaccatin III
Synonym	More Synonyms

9-Dihydro-13-acetylbaccatin III BiologicalActivity

Description	9-Dihydro-13-acetylbaccatin III (9-DHAB III) is an intermediate for taxol analog preparations. IC50 value:Target: There are a series of closely related natural organic compounds isolated from the Pacific yew tree (Taxus brevifolia) and related species. Taxols have exhibit antitumor agents. 9-Dihydro-13-acetylbaccatin III is an antineoplastic agent and an anti-cancer intermediate.
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Cancer
References	[1]. Li S, Zhang P, Zhang M, Fu C, Yu L. Functional analysis of a WRKY transcription factor involved in transcriptional activation of the DBAT gene in Taxus chinensis. Plant Biol (Stuttg). 2013 Jan;15(1):19-26. [2]. Naill MC, Kolewe ME, Roberts SC. Paclitaxel uptake and transport in Taxus cell suspension cultures. Biochem Eng J. 2012 Apr 15;63:50-56. [3]. Qayum M, Nisar M, Shah MR, et al. Analgesic and antiinflammatory activities of taxoids from Taxus wallichiana Zucc. Phytother Res. 2012 Apr;26(4):552-6. [4]. Kevin Walker and Rodney Croteau. Taxol biosynthesis: Molecular cloning of a benzoyl- CoA:taxane 2α-O-benzoyltransferase cDNA from Taxus and functional expression in Escherichia coli. PNAS, 2000 , 97（25）：13591-13596.

Description

9-Dihydro-13-acetylbaccatin III (9-DHAB III) is an intermediate for taxol analog preparations. IC50 value:Target: There are a series of closely related natural organic compounds isolated from the Pacific yew tree (Taxus brevifolia) and related species. Taxols have exhibit antitumor agents. 9-Dihydro-13-acetylbaccatin III is an antineoplastic agent and an anti-cancer intermediate.

Related Catalog

Signaling Pathways >>Others >>OthersResearch Areas >>Cancer

References

[1]. Li S, Zhang P, Zhang M, Fu C, Yu L. Functional analysis of a WRKY transcription factor involved in transcriptional activation of the DBAT gene in Taxus chinensis. Plant Biol (Stuttg). 2013 Jan;15(1):19-26.

[2]. Naill MC, Kolewe ME, Roberts SC. Paclitaxel uptake and transport in Taxus cell suspension cultures. Biochem Eng J. 2012 Apr 15;63:50-56.

[3]. Qayum M, Nisar M, Shah MR, et al. Analgesic and antiinflammatory activities of taxoids from Taxus wallichiana Zucc. Phytother Res. 2012 Apr;26(4):552-6.

[4]. Kevin Walker and Rodney Croteau. Taxol biosynthesis: Molecular cloning of a benzoyl- CoA:taxane 2α-O-benzoyltransferase cDNA from Taxus and functional expression in Escherichia coli. PNAS, 2000 , 97（25）：13591-13596.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	601.4±55.0 °C at 760 mmHg
Molecular Formula	C₃₃H₄₂O₁₂
Molecular Weight	630.68
Flash Point	193.0±25.0 °C
PSA	148.82000
LogP	0.69
Vapour Pressure	0.0±3.9 mmHg at 25°C
Index of Refraction	1.567
InChIKey	WPPPFZJNKLMYBW-FAEUQDRCSA-N
SMILES	CC(=O)OC1CC2(O)C(OC(=O)c3ccccc3)C3C4(OC(C)=O)COC4CC(O)C3(C)C(O)C(OC(C)=O)C(=C1C)C2(C)C
Storage condition	2-8°C

Safety Information

Hazard Codes	Xi
RIDADR	UN 1544
WGK Germany	3
Packaging Group	III
Hazard Class	6.1(b)

Synonyms

9-dehydro-13-acetylbaccatin III

7,9-Dideacetyl baccatin VI

Ddabvi

(1β,5β,7β,9α,10β,13α)-1,7,9-Trihydroxy-5,20-epoxytax-11-ene-4,10,13-triyl triacetate

CS-1097

7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-4,5,6,9,11,12b-hexol, 2a,3,4,4a,5,6,9,10,12,12a-decahydro-4a,8,13,13-tetramethyl-, 6,9,12b-triacetate, (2aR,4S,4aS,5R,6R,9S,11R,12aS,12bS)-

9-Dihydro-13-acetylbaccatin III

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