CAS 112-24-3|Triethylenetetramine
Introduction：Basic information about CAS 112-24-3|Triethylenetetramine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Triethylenetetramine | ||
|---|---|---|---|
| CAS Number | 112-24-3 | Molecular Weight | 146.234 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 266.5±0.0 °C at 760 mmHg |
| Molecular Formula | C6H18N4 | Melting Point | 12 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 143.3±0.0 °C |
| Symbol | GHS05, GHS07 | Signal Word | Danger |
Names
| Name | 2,2,2-tetramine |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 266.5±0.0 °C at 760 mmHg |
| Melting Point | 12 °C(lit.) |
| Molecular Formula | C6H18N4 |
| Molecular Weight | 146.234 |
| Flash Point | 143.3±0.0 °C |
| Exact Mass | 146.153152 |
| PSA | 76.10000 |
| LogP | -2.18 |
| Vapour density | ~5 (vs air) |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.490 |
| InChIKey | VILCJCGEZXAXTO-UHFFFAOYSA-N |
| SMILES | NCCNCCNCCN |
| Stability | Syable. Incompatible with strong oxidizing agents, strong acids. |
| Water Solubility | SOLUBLE |
| Freezing Point | 12℃ |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 468 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 350 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 5500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 805 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 9130 mg/kg
- SEX/DURATION :
- female 1-22 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - homeostasis Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 17430 mg/kg
- SEX/DURATION :
- female 1-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 8715 mg/kg
- SEX/DURATION :
- female 1-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - homeostasis
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- DOSE :
- 3667 mg/kg
- SEX/DURATION :
- female 10-56 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
MUTATION DATA - TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 1 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 320,31,1994 *** REVIEWS *** TOXICOLOGY REVIEW JJOMDZ JOM, Journal of Occupational Medicine. (American Occupational Medicine Assoc., 150 N. Wacker Dr., Chicago, IL 60606) V.10- 1968- Volume(issue)/page/year: 15,808,1973 TOXICOLOGY REVIEW CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 12,601,1978 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-SWEDEN:TWA 1 ppm (6 mg/m3);STEL 2 ppm (12 mg/m3) JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82037 No. of Facilities: 1982 (estimated) No. of Industries: 37 No. of Occupations: 44 No. of Employees: 14389 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82037 No. of Facilities: 7057 (estimated) No. of Industries: 96 No. of Occupations: 88 No. of Employees: 165511 (estimated) No. of Female Employees: 20726 (estimated)
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 1 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 320,31,1994 *** REVIEWS *** TOXICOLOGY REVIEW JJOMDZ JOM, Journal of Occupational Medicine. (American Occupational Medicine Assoc., 150 N. Wacker Dr., Chicago, IL 60606) V.10- 1968- Volume(issue)/page/year: 15,808,1973 TOXICOLOGY REVIEW CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 12,601,1978 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-SWEDEN:TWA 1 ppm (6 mg/m3);STEL 2 ppm (12 mg/m3) JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82037 No. of Facilities: 1982 (estimated) No. of Industries: 37 No. of Occupations: 44 No. of Employees: 14389 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82037 No. of Facilities: 7057 (estimated) No. of Industries: 96 No. of Occupations: 88 No. of Employees: 165511 (estimated) No. of Female Employees: 20726 (estimated)
Safety Information
| Symbol | GHS05, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H312-H314-H317-H412 |
| Precautionary Statements | P273-P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | C:Corrosive |
| Risk Phrases | R21;R34;R43;R52/53 |
| Safety Phrases | S26-S36/37/39-S45-S61 |
| RIDADR | UN 2259 8/PG 2 |
| WGK Germany | 2 |
| RTECS | YE6650000 |
| Packaging Group | II |
| Hazard Class | 8 |
| HS Code | 29212900 |
Customs
| HS Code | 2921290000 |
|---|---|
| Summary | 2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
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Synonyms
| EINECS 203-950-6 |
| 1,2-Ethanediamine, N,N-bis(2-aminoethyl)- |
| Trientine |
| N,N'-Bis(2-aminoethyl)-1,2-ethanediamine |
| N,N'-Bis(2-aminoethyl)ethane-1,2-diamine |
| TRIETHYLENETETRAAMINE |
| Triethylenetetramine (TETA) |
| N,N-Di(2-Aminoethyl)Ethylenediamine |
| Triethylenetetramine |
| DEH 24 EPH 925 |
| TETA |
| N,N'-Di(2-aminoethyl)ethylenediamine |
| 1,8-diamino-3,6-diazaoctane |
| 2,2,2-tetramine |
| N1,N1'-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) |
| MFCD00008169 |
| triethylene tetramine |
