Introduction：Basic information about CAS 51213-99-1|Clanfenur, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Clanfenur |
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| CAS Number | 51213-99-1 | Molecular Weight | 335.76 |
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| Density | 1.371g/cm3 | Boiling Point | / |
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| Molecular Formula | C16H15ClFN3O2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Clanfenur |
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| Synonym | More Synonyms |
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Clanfenur BiologicalActivity
| Description | Clanfenur is a substituted benzoylphenylurea, an analogue of the pesticide fenfluramide, with potential antineoplastic activity. Clanfenur can bind to the colchicine-binding site on β-tubulin, inhibit microtubule polymerization, and thus prevent tumor cell replication[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Microtubule/TubulinSignaling Pathways >>Cytoskeleton >>Microtubule/Tubulin |
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| References | [1]. J D Jonkman-de Vries, et al. Pharmaceutical development of a parenteral formulation of the investigational anticancer drug clanfenur. PDA J Pharm Sci Technol. 1997 Mar-Apr;51(2):89-95. |
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Chemical & Physical Properties
| Density | 1.371g/cm3 |
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| Molecular Formula | C16H15ClFN3O2 |
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| Molecular Weight | 335.76 |
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| Exact Mass | 335.08400 |
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| PSA | 61.44000 |
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| LogP | 3.97090 |
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| Index of Refraction | 1.64 |
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| InChIKey | SRLPZQAEBMZCIJ-UHFFFAOYSA-N |
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| SMILES | CN(C)c1cccc(F)c1C(=O)NC(=O)Nc1ccc(Cl)cc1 |
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| Storage condition | -20℃ |
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Safety Information
Customs
| HS Code | 2924299090 |
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| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| 1-(2-Dimethylaminoethyl)-piperazine |
| dimethyl(2-piperazinylethyl)amine |
| 1-(2-N,N-dimethylamino-6-fluorobenzoyl)-3-(4-chlorophenyl)urea |
| N,N-Dimethyl-2-(piperazin-1-yl)ethanamine |
| N-(CH2)2NMe2-piperazine |
| 4-(2-dimethylaminoethyl)piperazine |
| dimethyl(2-piperazin-1-yl-ethyl)amine |
| N-[[(4-chlorophenyl)amino]carbonyl]-2-(dimethylamino)-6-fluorobenzamide |
| 1-(2-N,N-dimethyl)-ethylpiperazine |
