CAS 38129-37-2|Bicyclomycin

Introduction：Basic information about CAS 38129-37-2|Bicyclomycin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Bicyclomycin BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Synonyms

Common Name	Bicyclomycin
CAS Number	38129-37-2	Molecular Weight	302.28
Density	1.57g/cm3	Boiling Point	786.6ºC at 760 mmHg
Molecular Formula	C₁₂H₁₈N₂O₇	Melting Point	/
MSDS	/	Flash Point	429.5ºC

Names

Name	bicozamycin
Synonym	More Synonyms

Bicyclomycin BiologicalActivity

Description	Bicyclomycin is an antibiotic. Bicyclomycin has anti-Bacterial activity against Gram-negative bacteria except Proteus and Pseudomonas aeruginosa[1].
Related Catalog	Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial
References	[1]. NISHIDA, M., et al. BICYCLOMYCIN, A NEW ANTIBIOTIC. The Journal of Antibiotics, 25(10), 582–593.

Chemical & Physical Properties

Density	1.57g/cm3
Boiling Point	786.6ºC at 760 mmHg
Molecular Formula	C₁₂H₁₈N₂O₇
Molecular Weight	302.28
Flash Point	429.5ºC
Exact Mass	302.11100
PSA	148.35000
Index of Refraction	1.632
InChIKey	WOUDXEYYJPOSNE-DSRXWYFFSA-N
SMILES	C=C1CCOC2(C(O)C(C)(O)CO)NC(=O)C1(O)NC2=O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DT7470000

CHEMICAL NAME :: Bicyclomycin

CAS REGISTRY NUMBER :: 38129-37-2

LAST UPDATED :: 199309

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C12-H18-N2-O7

MOLECULAR WEIGHT :: 302.32

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 25,569,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),235,1980

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 25,569,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),235,1980

Synonyms

antibiotic WS-4545

bicyclomycin

WS-4545

(1S)-6-hydroxy-5-methylene-1-((1S,2S)-1,2,3-trihydroxy-2-methyl-propyl)-2-oxa-7,9-diaza-bicyclo[4.2.2]decane-8,10-dione

BicozaMycin benzoate

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