CAS 51-65-0|4-Fluoro-L-phenylalanine
Introduction：Basic information about CAS 51-65-0|4-Fluoro-L-phenylalanine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-Fluoro-L-phenylalanine | ||
|---|---|---|---|
| CAS Number | 51-65-0 | Molecular Weight | 183.180 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 313.3±32.0 °C at 760 mmHg |
| Molecular Formula | C9H10FNO2 | Melting Point | 253-255ºC |
| MSDS | ChineseUSA | Flash Point | 143.3±25.1 °C |
| Symbol | GHS06 | Signal Word | Danger |
Names
| Name | 4-fluorophenylalanine |
|---|---|
| Synonym | More Synonyms |
4-Fluoro-L-phenylalanine BiologicalActivity
| Description | 2-Amino-3-(4-fluorophenyl)propanoic acid is a phenylalanine derivative[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| In Vitro | Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1]. |
| References | [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-814. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 313.3±32.0 °C at 760 mmHg |
| Melting Point | 253-255ºC |
| Molecular Formula | C9H10FNO2 |
| Molecular Weight | 183.180 |
| Flash Point | 143.3±25.1 °C |
| Exact Mass | 183.069550 |
| PSA | 63.32000 |
| LogP | 1.16 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.555 |
| InChIKey | XWHHYOYVRVGJJY-UHFFFAOYSA-N |
| SMILES | NC(Cc1ccc(F)cc1)C(=O)O |
| Stability | Stable. Combustible. Incompatible with strong oxidising agents. May be light sensitive. |
| Water Solubility | slightly soluble |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - rabbit Kidney
- DOSE/DURATION :
- 500 umol/L
- REFERENCE :
- ECREAL Experimental Cell Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.10- 1950- Volume(issue)/page/year: 36,92,1964
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - rabbit Kidney
- DOSE/DURATION :
- 500 umol/L
- REFERENCE :
- ECREAL Experimental Cell Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.10- 1950- Volume(issue)/page/year: 36,92,1964
Safety Information
| Symbol | GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H300 |
| Precautionary Statements | P264-P301 + P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| Hazard Codes | T:Toxic; |
| Risk Phrases | R25 |
| Safety Phrases | S45 |
| RIDADR | UN 2811 |
| WGK Germany | 3 |
| RTECS | AY6315000 |
| Packaging Group | III |
| HS Code | 2922499990 |
Customs
| HS Code | 2922499990 |
|---|---|
| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| EINECS 200-113-7 |
| p-Fluoro-DL-phenylalanine |
| S-(-)-p-Fluorophenylalanine |
| para-fluorophenylalanine |
| 4-Fluorophenylalanine |
| DL-4-Fluorophenylalanine |
| 4-Fluoro-DL-.β.-phenylalanine |
| L-4-Fluorophenylalanine |
| p-Fluoro-L-phenylalanine |
| L-4-Fluoro-Phenylalanine |
| (2S)-2-amino-3-(4-fluorophenyl)propanoic acid |
| 2-Amino-3-(4-fluorophenyl)propanoic acid |
| Phenylalanine, 4-fluoro- |
| 2-Amino-3-(4-fluorophenyl)propionic Acid |
| H-DL-Phe(4-F)-OH |
| 4-Fluoro-DL-phenylalanine |
| para-fluoro-l-phenylalanine |
| MFCD00002600 |
| (S)-2-Amino-3-(4-fluorophenyl)propanoic acid |
