CAS 147526-32-7|Pitavastatin calcium

Introduction：Basic information about CAS 147526-32-7|Pitavastatin calcium, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Pitavastatin calcium BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	Pitavastatin calcium
CAS Number	147526-32-7	Molecular Weight	440.49
Density	/	Boiling Point	692ºC at 760 mmHg
Molecular Formula	C₂₅H₂₃FNO_4.1/₂Ca	Melting Point	/
MSDS	/	Flash Point	372.3ºC

Names

Name	pitavastatin calcium
Synonym	More Synonyms

Pitavastatin calcium BiologicalActivity

Description	Pitavastatin Calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells.
Related Catalog	Signaling Pathways >>Autophagy >>AutophagySignaling Pathways >>Metabolic Enzyme/Protease >>HMG-CoA Reductase (HMGCR)Signaling Pathways >>Autophagy >>MitophagyResearch Areas >>Metabolic Disease
References	[1]. Mukhtar RY, et al. Pitavastatin. Int J Clin Pract. 2005 Feb;59(2):239-52. [2]. Kajinami K, et al. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor. Cardiovasc Drug Rev. 2003 Fall;21(3):199-215.

Description

Pitavastatin Calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells.

Related Catalog

Signaling Pathways >>Autophagy >>AutophagySignaling Pathways >>Metabolic Enzyme/Protease >>HMG-CoA Reductase (HMGCR)Signaling Pathways >>Autophagy >>MitophagyResearch Areas >>Metabolic Disease

References

[1]. Mukhtar RY, et al. Pitavastatin. Int J Clin Pract. 2005 Feb;59(2):239-52.

[2]. Kajinami K, et al. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor. Cardiovasc Drug Rev. 2003 Fall;21(3):199-215.

Chemical & Physical Properties

Boiling Point	692ºC at 760 mmHg
Molecular Formula	C₂₅H₂₃FNO_4.1/₂Ca
Molecular Weight	440.49
Flash Point	372.3ºC
PSA	186.96000
LogP	6.36680
InChIKey	AMUDYCAFPCQTAZ-NRFPMOEYSA-N
SMILES	O=C(O)CC(O)CC(O)C=Cc1c(C2CC2)nc2ccccc2c1-c1ccc(F)cc1.[Ca]
Storage condition	-20°C

Safety Information

Hazard Codes	Xi
HS Code	2933499090

Customs

HS Code	2933499090
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-, calcium salt, (3R,5S,6E)- (2:1)

Pitavastatin Calcium

Livalo

Calcium bis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoate}

MFCD01937979

UNII-IYD54XEG3W

Pitavastatin (Calcium)

calcium,(E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate

Livazo

(+)-Monocalciumbis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoate}

(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxy-hept-6-enoic acid

NK-104

[3H]-Pitavastatin

Alipza

Pitavastatin hemicalcium

Nisvastatin

[14C]-Pitavastatin

(+)-Monocalcium bis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoate}

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