Introduction：Basic information about CAS 143537-62-6|N-(3-Oxohexanoyl)homoserine lactone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-(3-Oxohexanoyl)homoserine lactone |
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| CAS Number | 143537-62-6 | Molecular Weight | 213.230 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 482.9±45.0 °C at 760 mmHg |
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| Molecular Formula | C10H15NO4 | Melting Point | / |
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| MSDS | USA | Flash Point | 245.9±28.7 °C |
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Names
| Name | N-(.β.-ketocaproyl)-L-Homoserine lactone |
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| Synonym | More Synonyms |
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N-(3-Oxohexanoyl)homoserine lactone BiologicalActivity
| Description | N-(β-ketocaproyl)-L-Homoserine lactone is a component of quorum regulatory sensing[1]. |
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| Related Catalog | Research Areas >>InfectionResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. Welch M, et al. N-acyl homoserine lactone binding to the CarR receptor determines quorum-sensing specificity in Erwinia. EMBO J. 2000 Feb 15;19(4):631-41. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 482.9±45.0 °C at 760 mmHg |
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| Molecular Formula | C10H15NO4 |
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| Molecular Weight | 213.230 |
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| Flash Point | 245.9±28.7 °C |
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| Exact Mass | 213.100113 |
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| PSA | 72.47000 |
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| LogP | -1.17 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.486 |
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| InChIKey | YRYOXRMDHALAFL-QMMMGPOBSA-N |
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| SMILES | CCCC(=O)CC(=O)NC1CCOC1=O |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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Articles2
More Articles
| Cell adhesion, ammonia removal and granulation of autotrophic nitrifying sludge facilitated by N-acyl-homoserine lactones. Bioresour. Technol. 196 , 550-8, (2015) In this study, six N-acyl-homoserine lactone (AHL) molecules (C6-HSL, C8-HSL, C10-HSL, 3-oxo-C6-HSL, 3-oxo-C8-HSL and 3-oxo-C10-HSL) were each dosed into a bioreactor and seeded using autotrophic nitr... | |
| Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators. Bioorg. Med. Chem. Lett. 18 , 5978-81, (2008) A focused library of N-aryl l-homoserine lactones was designed around known lactone leads and evaluated for antagonistic and agonistic activity against quorum-sensing receptors in Agrobacterium tumefa... | |
Synonyms
| 3-Oxo-N-(2-oxotetrahydrofuran-3-yl)hexanamide |
| N-(3-Oxohexanoyl)homoserine lactone |
| N-(3-Oxohexanoyl)-3-aminodihydro-2(3H)-furanone |
| Hexanamide, 3-oxo-N-(tetrahydro-2-oxo-3-furanyl)- |
| 3-Oxo-N-(tetrahydro-2-oxo-3-furanyl)hexanamide |
| 3-Oxo-N-(2-oxotetrahydro-3-furanyl)hexanamide |
| N-(β-ketocaproyl)-DL-homoserine lactone |
| N-(BETA-KETOCAPROYL)-DL-HOMOSERINE LACTONE |
