Introduction：Basic information about CAS 117857-93-9|(2S)-ISOPROPYLPIPERAZINE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (2S)-ISOPROPYLPIPERAZINE |
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| CAS Number | 117857-93-9 | Molecular Weight | 159.14000 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C6H9NO4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | (2S,1′S,2′S)-2-(Carboxycyclopropyl)glycine |
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| Synonym | More Synonyms |
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(2S)-ISOPROPYLPIPERAZINE BiologicalActivity
| Description | L-CCG-I is an extended isomer of conformationally restricted glutamate analog. L-CCG-I also is a potent agonist for mGluR2 with an EC50 value of 0.3 nM. L-CCG-I can be used for the research of mGluR family[1]. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>mGluRResearch Areas >>Metabolic Disease |
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| Target | mGluR2:0.3 nM (EC50) |
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| In Vitro | L-CCG-I 对 mGluR2 具有活性，EC50 值为 0.3 nM[1]。 L-CCG-I 有效刺激表达 mGluR1 的细胞中的磷脂酰肌醇水解[1]。 L-CCG-I 可抑制毛喉素刺激的腺苷 3':5'-环磷酸（环AMP）在 mGluR2 表达细胞中的积累[1]。 L-CCG-I 引起 mGluR4 毛喉素刺激的环 AMP 生成特征的抑制[1]。 |
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| References | [1]. Y Hayashi, et al. Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells. Br J Pharmacol. 1992 Oct;107(2):539-43. |
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Chemical & Physical Properties
| Molecular Formula | C6H9NO4 |
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| Molecular Weight | 159.14000 |
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| Exact Mass | 159.05300 |
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| PSA | 100.62000 |
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| InChIKey | GZOVEPYOCJWRFC-HZLVTQRSSA-N |
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| SMILES | NC(C(=O)O)C1CC1C(=O)O |
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Safety Information
Synonyms
| (2s,1's,2's)-2-(carboxycyclopropyl)glycine |
| MFCD00216830 |
