Introduction：Basic information about CAS 122332-18-7|Mivobulin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Mivobulin |
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| CAS Number | 122332-18-7 | Molecular Weight | 315.40700 |
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| Density | 1.36 | Boiling Point | 483ºC at 760mmHg |
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| Molecular Formula | C17H19N5O2 | Melting Point | / |
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| MSDS | / | Flash Point | 245.9ºC |
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Names
| Name | ethyl N-[(2S)-5-amino-2-methyl-3-phenyl-1,2-dihydropyrido[3,4-b]pyrazin-7-yl]carbamate |
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| Synonym | More Synonyms |
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Mivobulin BiologicalActivity
| Description | Mivobulin (NSC 613862) is a tubulin inhibitor, binds to tubulin in the region that overlaps the colchicine site, and inhibits tubulin polymerization. Mivobulin (NSC 613862) promotes the formation of abnormal polymers and a GTPase activity in the tubulin dimer. Anti-cancer activity[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Microtubule/TubulinSignaling Pathways >>Cytoskeleton >>Microtubule/Tubulin |
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| Target | Tubulin[1] |
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| References | [1]. Barbier P, et al. The active GTP- and ground GDP-liganded states of tubulin are distinguished by the binding of chiral isomers of ethyl 5-amino-2-methyl-1,2-dihydro-3-phenylpyrido[3,4-b]pyrazin-7-yl carbamate. Biochemistry. 1998 Jan 13;37(2):758-68. |
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Chemical & Physical Properties
| Density | 1.36 |
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| Boiling Point | 483ºC at 760mmHg |
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| Molecular Formula | C17H19N5O2 |
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| Molecular Weight | 315.40700 |
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| Flash Point | 245.9ºC |
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| Exact Mass | 315.18300 |
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| PSA | 57.61000 |
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| LogP | 2.90650 |
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| Vapour Pressure | 1.74E-09mmHg at 25°C |
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| Index of Refraction | 1.671 |
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| InChIKey | XXBDOTXPQDVHIP-JTQLQIEISA-N |
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| SMILES | CCOC(=O)Nc1cc2c(c(N)n1)N=C(c1ccccc1)C(C)N2 |
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Safety Information
Synonyms
| MIVOBULIN |
| mivobulin isethionate |
| UNII-96U5LG549X |
