CAS 12777-70-7|dryocrassin ABBA
Introduction：Basic information about CAS 12777-70-7|dryocrassin ABBA, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | dryocrassin ABBA | ||
|---|---|---|---|
| CAS Number | 12777-70-7 | Molecular Weight | 820.832 |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 1089.0±65.0 °C at 760 mmHg |
| Molecular Formula | C43H48O16 | Melting Point | / |
| MSDS | / | Flash Point | 626.1±30.8 °C |
Names
| Name | 2-acetyl-4-[[3-[[3-[(5-acetyl-2,6-dihydroxy-3,3-dimethyl-4-oxocyclohexa-1,5-dien-1-yl)methyl]-5-butanoyl-2,4,6-trihydroxyphenyl]methyl]-5-butanoyl-2,4,6-trihydroxyphenyl]methyl]-3,5-dihydroxy-6,6-dimethylcyclohexa-2,4-dien-1-one |
|---|---|
| Synonym | More Synonyms |
dryocrassin ABBA BiologicalActivity
| Description | Dryocrassin ABBA (Dryocrassin) is a flavonoid natural product derived from Dryopteris crassirhizoma, with antiviral and antibacterial activities[1][2]. Dryocrassin ABBA exhibits antiviral activity against H5N1 avian influenza virus[1]. Dryocrassin ABBA inhibits the coagulase activity of Staphylococcus aureus vWbp[3]. Dryocrassin ABBA suppresses immunostimulatory function of dendritic cells and prolongs skin allograft survival[4]. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>Influenza VirusResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
| Target | H5N1 avian influenza virus[1] |
| References | [1]. Ou C, et al. Dryocrassin ABBA, a novel active substance for use against amantadine-resistant H5N1 avian influenza virus. Front Microbiol. 2015 Jun 16;6:592. [2]. Zhang B, et al. Molecular Mechanism of the Flavonoid Natural Product Dryocrassin ABBA against Staphylococcus aureus Sortase A. Molecules. 2016 Oct 26;21(11). [3]. Li B, et al. An Inhibitory Effect of Dryocrassin ABBA on Staphylococcus aureus vWbp That Protects Mice From Pneumonia. Front Microbiol. 2019 Jan 23;10:7. [4]. Fu RH, et al. Dryocrassin suppresses immunostimulatory function of dendritic cells and prolongs skin allograft survival. Cell Transplant. 2014;23(4-5):641-56. |
Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 1089.0±65.0 °C at 760 mmHg |
| Molecular Formula | C43H48O16 |
| Molecular Weight | 820.832 |
| Flash Point | 626.1±30.8 °C |
| Exact Mass | 820.294250 |
| PSA | 304.72000 |
| LogP | 8.08 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.673 |
| InChIKey | PRVKSKWNDSLRBY-UHFFFAOYSA-N |
| SMILES | CCCC(=O)c1c(O)c(CC2=C(O)C(C)(C)C(=O)C(C(C)=O)=C2O)c(O)c(Cc2c(O)c(CC3=C(O)C(C)(C)C(=O)C(C(C)=O)=C3O)c(O)c(C(=O)CCC)c2O)c1O |
Synonyms
| 2,2'-{Methylenebis[(5-butyryl-2,4,6-trihydroxy-3,1-phenylene)methylene]}bis(6-acetyl-3,5-dihydroxy-4,4-dimethyl-2,5-cyclohexadien-1-one) |
| 2,5-Cyclohexadien-1-one,2,2'-(methylenebis((2,4,6-trihydroxy-5-(1-oxobutyl)-3,1-phenylene)methylene)bis(6-acetyl-3,5-dihydroxy |
| Y0072 |
| 4,4'-{Methylenebis[(5-butyryl-2,4,6-trihydroxy-3,1-phenylene)methylene]}bis(2-acetyl-3,5-dihydroxy-6,6-dimethyl-2,4-cyclohexadien-1-one) |
| 2,5-Cyclohexadien-1-one, 2,2'-[methylenebis[[2,4,6-trihydroxy-5-(1-oxobutyl)-3,1-phenylene]methylene]]bis[6-acetyl-3,5-dihydroxy-4,4-dimethyl- |
| tetraalbaspidin-ABBA |
| 2,4-Cyclohexadien-1-one, 4,4'-[methylenebis[[2,4,6-trihydroxy-5-(1-oxobutyl)-3,1-phenylene]methylene]]bis[2-acetyl-3,5-dihydroxy-6,6-dimethyl- |
| Dryocrassin ABBA |
| Dryocrassin |
