Introduction：Basic information about CAS 122413-01-8|Paederosidic acid methyl ester, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Paederosidic acid methyl ester |
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| CAS Number | 122413-01-8 | Molecular Weight | 478.467 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | 711.2±70.0 °C at 760 mmHg |
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| Molecular Formula | C19H26O12S | Melting Point | / |
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| MSDS | / | Flash Point | 383.9±35.7 °C |
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Names
| Name | Methyl (1S,4aS,5S,7aS)-1-(β-D-glucopyranosyloxy)-5-hydroxy-7-({[( methylsulfanyl)carbonyl]oxy}methyl)-1,4a,5,7a-tetrahydrocyclopent a[c]pyran-4-carboxylate |
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| Synonym | More Synonyms |
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Paederosidic acid methyl ester BiologicalActivity
| Description | Paederosidic acid methyl ester is a ATP‐sensitive K+ channel activator, isolated from P. scandens. Paederosidic acid methyl ester exhibits significant central analgesic activity, and enhances the threshold of pain by activating ATP‐sensitive K+ channel in the brain and spinal cord level[1]. |
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| Related Catalog | Research Areas >>Neurological DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>Potassium Channel |
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| Target | IC50: K+ channel[1] |
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| References | [1]. Chen YF,et al.Possible mechanism involved in the antinociceptive activity of dimer of paederosidic acid and paederosidic acid methyl ester in mice.CNS Neurosci Ther. 2014 Feb;20(2):188-90. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Boiling Point | 711.2±70.0 °C at 760 mmHg |
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| Molecular Formula | C19H26O12S |
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| Molecular Weight | 478.467 |
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| Flash Point | 383.9±35.7 °C |
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| Exact Mass | 478.114502 |
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| PSA | 206.74000 |
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| LogP | -1.72 |
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| Vapour Pressure | 0.0±5.2 mmHg at 25°C |
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| Index of Refraction | 1.634 |
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| InChIKey | JNDNZIPLLDTLQK-DILZHRMZSA-N |
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| SMILES | COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C2C(COC(=O)SC)=CC(O)C12 |
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Safety Information
Synonyms
| Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-[[[(methylthio)carbonyl]oxy]methyl]-, methyl ester, (1S,4aS,5R,7aS)- |
| Methyl (1S,4aS,5S,7aS)-1-(β-D-glucopyranosyloxy)-5-hydroxy-7-({[(methylsulfanyl)carbonyl]oxy}methyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate |
| paederosidic acid methyl ester |
| Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-[[[(methylthio)carbonyl]oxy]methyl]-, methyl ester, (1S,4aS,5S,7aS)- |
| Methyl (1S,4aS,5R,7aS)-1-(β-D-glucopyranosyloxy)-5-hydroxy-7-({[(methylsulfanyl)carbonyl]oxy}methyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate |
