CAS 115900-75-9|1,2-diethyl-3-hydroxypyridin-4-one

CHEMICAL IDENTIFICATION

RTECS NUMBER :

UU7785800

CHEMICAL NAME :

4(1H)-Pyridinone, 1,2-diethyl-3-hydroxy-

CAS REGISTRY NUMBER :

115900-75-9

LAST UPDATED :

199709

DATA ITEMS CITED :

4

MOLECULAR FORMULA :

C9-H13-N-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

875 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

BLOOAW Blood. (Grune & Stratton, Inc., 465 S. Lincoln Dr., Troy, MO 63379) V.1- 1946- Volume(issue)/page/year: 76,2389,1990 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

52 gm/kg/52W-I

TOXIC EFFECTS :

Related to Chronic Data - death

REFERENCE :

MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 28(Suppl A),81,1992

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

42 gm/kg/15W-C

TOXIC EFFECTS :

Liver - other changes Biochemical - Metabolism (Intermediary) - porphyrin including bile pigments

REFERENCE :

BLOOAW Blood. (Grune & Stratton, Inc., 465 S. Lincoln Dr., Troy, MO 63379) V.1- 1946- Volume(issue)/page/year: 89,1045,1997

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

12 gm/kg/12W-I

TOXIC EFFECTS :

Liver - other changes Related to Chronic Data - death

REFERENCE :

BLOOAW Blood. (Grune & Stratton, Inc., 465 S. Lincoln Dr., Troy, MO 63379) V.1- 1946- Volume(issue)/page/year: 78,2727,1991