CAS 157698-32-3|Tamoxifen-d5

Introduction：Basic information about CAS 157698-32-3|Tamoxifen-d5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Tamoxifen-d5 BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Tamoxifen-d5
CAS Number	157698-32-3	Molecular Weight	376.54500
Density	1.057g/cm3	Boiling Point	482.3ºC at 760mmHg
Molecular Formula	C₂₆H₂₄D₅NO	Melting Point	/
MSDS	/	Flash Point	140ºC

Names

Name	N,N-dimethyl-2-[4-[(Z)-3,3,4,4,4-pentadeuterio-1,2-diphenylbut-1-enyl]phenoxy]ethanamine
Synonym	More Synonyms

Tamoxifen-d5 BiologicalActivity

Description	Tamoxifen-d5 (ICI 47699-d5) is a deuterium labeled Tamoxifen. Tamoxifen (ICI 47699) is a selective estrogen receptor modulator (SERM). Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity[1][2].
Related Catalog	Signaling Pathways >>Others >>Estrogen Receptor/ERRSignaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>CancerSignaling Pathways >>Metabolic Enzyme/Protease >>HSPSignaling Pathways >>Autophagy >>AutophagySignaling Pathways >>Cell Cycle/DNA Damage >>HSP
Target	Estrogen receptor HSP90
References	[1]. Osborne CK. Tamoxifen in the treatment of breast cancer. N Engl J Med. 1998 Nov 26;339(22):1609-18. [2]. Zhao R, et al. Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity. PLoS One. 2010 Apr 1;5(4):e9934.

Chemical & Physical Properties

Density	1.057g/cm3
Boiling Point	482.3ºC at 760mmHg
Molecular Formula	C₂₆H₂₄D₅NO
Molecular Weight	376.54500
Flash Point	140ºC
Exact Mass	376.25600
PSA	12.47000
LogP	5.99610
Vapour Pressure	1.85E-09mmHg at 25°C
Index of Refraction	1.582
InChIKey	NKANXQFJJICGDU-FUYVPVGLSA-N
SMILES	CCC(=C(c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1

Synonyms

(E/Z)-Mammaton-d5

Novaldex-d5

Z-Tamoxifen-d5

Mammaton-d5

(E/Z)-Novaldex-d5

(E/Z)-Tamoxifen-d5

trans-Tamoxifen-d5

Tamoxifen-d5

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