Introduction：Basic information about CAS 1217449-45-0|Aflatoxin B1-13C17, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Aflatoxin B1-13C17 |
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| CAS Number | 1217449-45-0 | Molecular Weight | 329.15 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | 13C17H12O6 | Melting Point | / |
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| MSDS | USA | Flash Point | 2℃ |
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| Symbol |
GHS02, GHS07 | Signal Word | Danger |
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Names
| Name | Aflatoxin B1-13C17 solution |
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| Synonym | More Synonyms |
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Aflatoxin B1-13C17 BiologicalActivity
| Description | Aflatoxin B1-13C17 is 13C- and 15N-labeled Aflatoxin B1 (HY-N6615). Aflatoxin B1 (AFB1) is a Class 1A carcinogen, which is a secondary metabolite of Aspergillus flavus and A. parasiticus. Aflatoxin B1 (AFB1) mainly induces the transversion of G-->T in the third position of codon 249 of the p53 tumor suppressor gene, resulting in mutation[1][2][3]. |
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| Related Catalog | Research Areas >>Cancer |
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| In Vitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。 |
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| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. |
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Chemical & Physical Properties
| Molecular Formula | 13C17H12O6 |
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| Molecular Weight | 329.15 |
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| Flash Point | 2℃ |
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| Exact Mass | 329.12000 |
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| PSA | 74.97000 |
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| LogP | 2.27650 |
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| InChIKey | OQIQSTLJSLGHID-DENWKYDXSA-N |
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| SMILES | COc1cc2c(c3oc(=O)c4c(c13)CCC4=O)C1C=COC1O2 |
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| Storage condition | ?20°C |
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Safety Information
| Symbol |
GHS02, GHS07 |
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| Signal Word | Danger |
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| Hazard Statements | H225-H302 + H312 + H332-H319 |
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| Precautionary Statements | P210-P280-P305 + P351 + P338 |
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| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
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| Hazard Codes | F,Xn |
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| Risk Phrases | 11-20/21/22-36 |
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| Safety Phrases | 16-36/37 |
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| RIDADR | UN 1648 3 / PGII |
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Synonyms
| Fully 13C-labelled Aflatoxin B1 |
