CAS 14259-46-2|Narirutin
| Common Name | Narirutin | ||
|---|---|---|---|
| CAS Number | 14259-46-2 | Molecular Weight | 580.535 |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 924.3±65.0 °C at 760 mmHg |
| Molecular Formula | C27H32O14 | Melting Point | 152-190ºC |
| MSDS | ChineseUSA | Flash Point | 307.3±27.8 °C |
Names
| Name | narirutin |
|---|---|
| Synonym | More Synonyms |
Narirutin BiologicalActivity
| Description | Narirutin, one of the active constituents isolated from Citrus unshiu, has antioxidant and anti-inflammatory activities. Narirutin is a shikimate kinase inhibitor with anti-tubercular potency[1][2]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
| References | [1]. Sahu PK, et al. Structure-based Discovery of Narirutin as a Shikimate Kinase Inhibitor with Anti-tubercular Potency.Curr Comput Aided Drug Des. 2019 Oct 25. [2]. Funaguchi N, et al. Narirutin inhibits airway inflammation in an allergic mouse model.Clin Exp Pharmacol Physiol. 2007 Aug;34(8):766-70. |
Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 924.3±65.0 °C at 760 mmHg |
| Melting Point | 152-190ºC |
| Molecular Formula | C27H32O14 |
| Molecular Weight | 580.535 |
| Flash Point | 307.3±27.8 °C |
| Exact Mass | 580.179199 |
| PSA | 225.06000 |
| LogP | 2.07 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.708 |
| InChIKey | HXTFHSYLYXVTHC-AJHDJQPGSA-N |
| SMILES | CC1OC(OCC2OC(Oc3cc(O)c4c(c3)OC(c3ccc(O)cc3)CC4=O)C(O)C(O)C2O)C(O)C(O)C1O |
Safety Information
| Safety Phrases | 22-24/25 |
|---|---|
| RIDADR | NONH for all modes of transport |
| HS Code | 29389090 |
Articles2
More Articles| Berry and Citrus Phenolic Compounds Inhibit Dipeptidyl Peptidase IV: Implications in Diabetes Management. Evid. Based. Complement. Alternat. Med. 2013 , 479505, (2013) Beneficial health effects of fruits and vegetables in the diet have been attributed to their high flavonoid content. Dipeptidyl peptidase IV (DPP-IV) is a serine aminopeptidase that is a novel target ... | |
| Huanglongbing modifies quality components and flavonoid content of 'Valencia' oranges. J. Sci. Food Agric. 96 , 73-8, (2016) In order to evaluate the effect of citrus greening disease, or Huanglongbing (HLB), on quality components and flavonoid contents of 'Valencia' oranges, fruit from non-infected trees (control), from in... |
Synonyms
| (2S)-5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl-6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside |
| (2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranoside |
| ISONARINGIN |
| Isonaringenin |
| Naringenin 7-O-rutinoside |
| 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)- |
| Naringenin-7-rutinoside |
| (2S)-5-Hydroxy-2-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl]oxy}-2,3-dihydro-4H-chromen-4-one |
| Narirutin |
| (2S)-5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside |
| (2S)-5-Hydroxy-2-(4-hydroxyphényl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-méthyltétrahydro-2H-pyran-2-yl]oxy}méthyl)tétrahydro-2H-pyran-2-yl]oxy}-2,3-dihydro-4H-chromén-4-one |
| Naringenin 7-rutinoside |
| (S)-7-((6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| naringenin-7-O-rutinoside |
| Apigenin-7-rutinosid |
| (2S)-5-Hydroxy-2-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl]oxy}-2,3-dihydro-4H-chromen-4-on |
