Introduction：Basic information about CAS 199798-84-0|Elocalcitol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Elocalcitol |
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| CAS Number | 199798-84-0 | Molecular Weight | 442.65 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C29H43FO2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | (1R,3E,5S)-3-[(2E)-2-[(3aS,7aS)-1-[(E,2S)-6-ethyl-6-hydroxyoct-4-en-2-yl]-7a-methyl-3a,5,6,7-tetrahydro-3H-inden-4-ylidene]ethylidene]-5-fluoro-4-methylidenecyclohexan-1-ol |
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| Synonym | More Synonyms |
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Elocalcitol BiologicalActivity
| Description | Elocalcitol (BXL-628) is a selective, orally active vitamin D receptor (VDR) agonist. Elocalcitol shows anti-inflammatory activity. Elocalcitol inhibits growth of prostate cancer cells[1][2]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Vitamin D Related >>VD/VDRResearch Areas >>Inflammation/Immunology |
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| References | [1]. Mariani M, et al. The selective vitamin D receptor agonist, elocalcitol, reduces endometriosis development in a mouse model by inhibiting peritoneal inflammation. Hum Reprod. 2012 Jul;27(7):2010-9. [2]. Marchiani S, et al. The vitamin D analogue BXL-628 inhibits growth factor-stimulated proliferation and invasion of DU145 prostate cancer cells. J Cancer Res Clin Oncol. 2006 Jun;132(6):408-16. |
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Chemical & Physical Properties
| Molecular Formula | C29H43FO2 |
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| Molecular Weight | 442.65 |
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| Exact Mass | 442.32500 |
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| PSA | 40.46000 |
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| LogP | 7.15820 |
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| InChIKey | LRLWXBHFPGSUOX-RNLCVJHJSA-N |
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| SMILES | C=C1C(=CC=C2CCCC3(C)C(C(C)CC=CC(O)(CC)CC)=CCC23)CC(O)CC1F |
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Synonyms
