Introduction：Basic information about CAS 80-74-0|sulfisoxazole acetyl (200 mg), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | sulfisoxazole acetyl (200 mg) |
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| CAS Number | 80-74-0 | Molecular Weight | 309.34100 |
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| Density | 1.404g/cm3 | Boiling Point | / |
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| Molecular Formula | C13H15N3O4S | Melting Point | 193-194° |
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| MSDS | / | Flash Point | / |
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Names
| Name | N-(4-aminophenyl)sulfonyl-N-(3,4-dimethyl-1,2-oxazol-5-yl)acetamide |
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| Synonym | More Synonyms |
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sulfisoxazole acetyl (200 mg) BiologicalActivity
| Description | Sulfisoxazole acetyl (N1-Acetylsulfisoxazole), a Sulfisoxazole derivative, is an orally active dihydropteroate synthase inhibitor. Sulfisoxazole acetyl has an antibacterial action[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| In Vitro | As with other sulfonamides, the antibacterial action of Sulfisoxazole acetyl (N1-Acetylsulfisoxazole) is attributable to inhibiting dihydropteroate synthase, a key enzyme in folate synthesis in bacteria. Sulfisoxazole acetyl is known to be transformed primarily to sulfisoxazole, partly to N4-acetyl sulfisoxazole (N4AS), and likely also to diacetyl sulfisoxazole (DAS) and other compounds[1]. |
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| References | [1]. Eunyoung Kim, et al. Simultaneous determination of N(1)-acetyl sulfisoxazole and its metabolites, and relative bioavailability compare to sulfisoxazole in rats. J Pharm Biomed Anal. 2016 Sep 10;129:117-120. |
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Chemical & Physical Properties
| Density | 1.404g/cm3 |
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| Melting Point | 193-194° |
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| Molecular Formula | C13H15N3O4S |
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| Molecular Weight | 309.34100 |
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| Exact Mass | 309.07800 |
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| PSA | 114.88000 |
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| LogP | 3.27740 |
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| Index of Refraction | 1.611 |
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| InChIKey | JFNWFXVFBDDWCX-UHFFFAOYSA-N |
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| SMILES | CC(=O)N(c1onc(C)c1C)S(=O)(=O)c1ccc(N)cc1 |
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Safety Information
| RIDADR | NONH for all modes of transport |
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| HS Code | 2935009090 |
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Customs
| HS Code | 2935009090 |
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| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
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Synonyms
| GANTRISIN PEDIATRIC |
| Acetyl-(3,4-dimethyl-isoxazol-5-yl)-sulfanilyl-amin |
| Sulfisoxazole acetyl |
| Lipo Gantrisin |
| N-(4-amino-benzenesulfonyl)-N-(3,4-dimethyl-isoxazol-5-yl)-acetamide |
| N-3,4-dimethylisoxazol-5-yl-N-sulfanilylacetamide |
| UNII-WBT5QH3KED |
| EINECS 201-305-3 |
| Sulfisoxazole acetal |
| acetylsulfafurazole |
| ACETYL SULFISOXAZOLE |
