Introduction：Basic information about CAS 145667-75-0|Latanoprost lactone diol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Latanoprost lactone diol |
|---|
| CAS Number | 145667-75-0 | Molecular Weight | 304.381 |
|---|
| Density | 1.2±0.1 g/cm3 | Boiling Point | 523.0±35.0 °C at 760 mmHg |
|---|
| Molecular Formula | C18H24O4 | Melting Point | 69-71ºC |
|---|
| MSDS | / | Flash Point | 190.3±19.4 °C |
|---|
Names
| Name | (3aR,4R,5R,6aS)-5-hydroxy-4-[(3R)-3-hydroxy-5-phenylpentyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one |
|---|
| Synonym | More Synonyms |
|---|
Latanoprost lactone diol BiologicalActivity
| Description | Latanoprost lactone diol is an intermediate in the synthesis of Latanoprost. Latanoprost is a prostaglandin F2α analogue and an agonist for the FP prostanoid receptor, and lowers intraocular-pressure (IOP)[1]. |
|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>GPCR/G Protein >>Prostaglandin Receptor |
|---|
| References | [1]. Pauly A, et al. In vitro and in vivo comparative toxicological study of a new preservative-free latanoprost formulation. Invest Ophthalmol Vis Sci. 2012 Dec 13;53(13):8172-80. |
|---|
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|
| Boiling Point | 523.0±35.0 °C at 760 mmHg |
|---|
| Melting Point | 69-71ºC |
|---|
| Molecular Formula | C18H24O4 |
|---|
| Molecular Weight | 304.381 |
|---|
| Flash Point | 190.3±19.4 °C |
|---|
| Exact Mass | 304.167450 |
|---|
| PSA | 66.76000 |
|---|
| LogP | 0.60 |
|---|
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
|---|
| Index of Refraction | 1.568 |
|---|
| InChIKey | CQVHXVLSHMRWEC-UTSKFRMZSA-N |
|---|
| SMILES | O=C1CC2C(CC(O)C2CCC(O)CCc2ccccc2)O1 |
|---|
Synonyms
| (3aR,4R,5R,6aS)-5-Hydroxy-4-[(3R)-3-hydroxy-5-phenylpentyl]hexahydro-2H-cyclopenta[b]furan-2-one |
| LatanoprostLactoneDiol |
| 2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-[(3R)-3-hydroxy-5-phenylpentyl]-, (3aR,4R,5R,6aS)- |
