Introduction：Basic information about CAS 357645-16-0|7,8,9,9-Tetradehydroisolariciresinol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 7,8,9,9-Tetradehydroisolariciresinol |
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| CAS Number | 357645-16-0 | Molecular Weight | 356.369 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 587.4±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H20O6 | Melting Point | / |
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| MSDS | / | Flash Point | 211.0±23.6 °C |
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Names
| Name | 7,8,9,9-Tetradehydroisolariciresinol |
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| Synonym | More Synonyms |
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7,8,9,9-Tetradehydroisolariciresinol BiologicalActivity
| Description | Vitexin B-1 is an inhibitor of Bcl-2 and the agonist of Caspase. Vitexin B-1 has cytotoxic effect and induces apoptosis in MCF-7, ZR-75-1, MDA-MB-231, and COC1 cells with IC50s of 3.2, 2.1, 1.8 and 0.39 μM, respectively[1]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>Bcl-2 FamilyResearch Areas >>Cancer |
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| References | [1]. Zhou Y, et al. Vitexins, nature-derived lignan compounds, induce apoptosis and suppress tumor growth. Clin Cancer Res. 2009 Aug 15;15(16):5161-9. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 587.4±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H20O6 |
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| Molecular Weight | 356.369 |
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| Flash Point | 211.0±23.6 °C |
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| Exact Mass | 356.125977 |
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| PSA | 96.22000 |
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| LogP | 2.59 |
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| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
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| Index of Refraction | 1.664 |
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| InChIKey | PATMJUOZIPKVAS-YWZLYKJASA-N |
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| SMILES | COc1cc(C2c3cc(O)c(OC)cc3C=C(C=O)C2CO)ccc1O |
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Safety Information
Synonyms
| 2-Naphthalenecarboxaldehyde, 3,4-dihydro-6-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-, (3R,4S)- |
| (3R,4S)-6-Hydroxy-4-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-3,4-dihydro-2-naphthalenecarbaldehyde |
