CAS 514-07-8|Taraxerone

Introduction：Basic information about CAS 514-07-8|Taraxerone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Taraxerone BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Taraxerone
CAS Number	514-07-8	Molecular Weight	424.702
Density	1.0±0.1 g/cm3	Boiling Point	488.3±44.0 °C at 760 mmHg
Molecular Formula	C₃₀H₄₈O	Melting Point	/
MSDS	/	Flash Point	202.8±23.4 °C

Names

Name	Taraxerone
Synonym	More Synonyms

Taraxerone BiologicalActivity

Description	Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively[1].
Related Catalog	Signaling Pathways >>Metabolic Enzyme/Protease >>Aldehyde Dehydrogenase (ALDH)Research Areas >>Inflammation/Immunology
Target	EC50: 512.42 μM (ADH); 500.16 μM (ALDH)[1]
In Vivo	Taraxerone significantly lowers the plasma alcohol and acetaldehyde concentrations in mice. Compare to the control group, the ADH and ALDH expressions in the liver tissues are abruptly increased in the taraxerone-treated groups after ethanol exposure[1]. Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration[1].
References	[1]. Sung CK, et al. Taraxerone enhances alcohol oxidation via increases of alcohol dehyderogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities and gene expressions.Food Chem Toxicol. 2012 Jul;50(7):2508-14.

Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	488.3±44.0 °C at 760 mmHg
Molecular Formula	C₃₀H₄₈O
Molecular Weight	424.702
Flash Point	202.8±23.4 °C
Exact Mass	424.370514
PSA	17.07000
LogP	10.48
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.534
InChIKey	DBCAVZSSFGIHQZ-YLAYQGCQSA-N
SMILES	CC1(C)CCC2(C)CC=C3C(C)(CCC4C3(C)CCC3C(C)(C)C(=O)CCC34C)C2C1

Safety Information

Hazard Codes	Xi

Synonyms

3(2H)-Picenone, 1,4,4a,5,6,6a,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-octadecahydro-4,4,6a,8a,11,11,12b,14b-octamethyl-, (4aR,6aR,8aR,12aR,12bS,14aR,14bR)-

(4aR,6aR,8aR,12aR,12bS,14aR,14bR)-4,4,6a,8a,11,11,12b,14b-Octamethyl-1,4,4a,5,6,6a,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-octadecahydro-3(2H)-picenone

(4aR,6aR,8aR,12aR,12bS,14aR,14bR)-4,4,6a,8a,11,11,12b,14b-octamethyl-1,4,4a,5,6,6a,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-octadecahydropicen-3(2H)-one

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