CAS 15231-41-1|Boc-C2-NH2

Introduction:Basic information about CAS 15231-41-1|Boc-C2-NH2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBoc-C2-NH2
CAS Number15231-41-1Molecular Weight145.19900
Density/Boiling Point192.3°C
Molecular FormulaC7H15NO2Melting Point/
MSDS/Flash Point/

Names

Nametert-Butyl 3-aminopropanoate
SynonymMore Synonyms

Boc-C2-NH2 BiologicalActivity

DescriptionBoc-C2-NH2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

Alkyl/ether

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Boiling Point192.3°C
Molecular FormulaC7H15NO2
Molecular Weight145.19900
Exact Mass145.11000
PSA52.32000
LogP1.37720
InChIKeyZJXHVYSDMUKUCA-UHFFFAOYSA-N
SMILESCC(C)(C)OC(=O)CCN
Storage condition2-8°C

Safety Information

Hazard CodesXi
HS Code2922499990

Customs

HS Code2922499990
SummaryHS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Synonyms

tert-butyl 3-aminopropanoate
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