Introduction：Basic information about CAS 14270-73-6|5'-Trt-2'-dU, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5'-Trt-2'-dU |
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| CAS Number | 14270-73-6 | Molecular Weight | 470.52 |
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| Density | 1.3g/cm3 | Boiling Point | / |
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| Molecular Formula | C28H26N2O5 | Melting Point | 204-205 °C |
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| MSDS | / | Flash Point | / |
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Names
| Name | 5'-O-Trityl-2'-deoxyuridine |
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| Synonym | More Synonyms |
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5'-Trt-2'-dU BiologicalActivity
| Description | 5’-O-Triphenylmethyl-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.3g/cm3 |
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| Melting Point | 204-205 °C |
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| Molecular Formula | C28H26N2O5 |
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| Molecular Weight | 470.52 |
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| Exact Mass | 470.18400 |
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| PSA | 93.55000 |
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| LogP | 3.19370 |
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| Index of Refraction | 1.63 |
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Safety Information
Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 1-[(2R,4S,5R)-4-hydroxy-5-(trityloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
| 5'-Trt-2'-dU |
