CAS 144-68-3|Zeaxanthin

Introduction:Basic information about CAS 144-68-3|Zeaxanthin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameZeaxanthin
CAS Number144-68-3Molecular Weight568.871
Density1.0±0.1 g/cm3Boiling Point711.4±55.0 °C at 760 mmHg
Molecular FormulaC40H56O2Melting Point203-2050C
MSDSChineseUSAFlash Point273.4±26.1 °C

Names

Namezeaxanthin
SynonymMore Synonyms

Zeaxanthin BiologicalActivity

DescriptionZeaxanthin, a diet-obtained carotenoid, presents in the macula region of the eye. Zeaxanthin shows antioxidant effects[1][2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
In VitroMuch of the Lutein and Zeaxanthin in the leaves of plants is protein-bound.In fruits and flower petals, the xanthophylls are esterified and are concentrated into chromoplasts where they are found to be solubilized in the membranes. In humans and higher animals, Lutein and Zeaxanthin are accumulated in lipophilic tissues such as adipose tissue and are carried in the blood by the lipoproteins, probably in a nonspecific manner similar to cholesterol. Lutein and Zeaxanthin are distributed equally between LDL and HDL fractions in human blood, in contrast to the hydrocarbon carotenoids that are preferentially found in LDL fractions, up to 75%[3].
References

[1]. Bone RA, et al. Distribution of lutein and zeaxanthin stereoisomers in the human retina. Exp Eye Res. 1997 Feb;64(2):211-8.

[2]. Elbaz-Hayoun S, et al. Evaluation of antioxidant treatments for the modulation of macrophage function in the context of retinal degeneration. Mol Vis. 2019 Sep 5;25:479-488.

[3]. Krinsky NI, et al. Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye.Annu Rev Nutr. 2003;23:171-201.

Chemical & Physical Properties

Density1.0±0.1 g/cm3
Boiling Point711.4±55.0 °C at 760 mmHg
Melting Point203-2050C
Molecular FormulaC40H56O2
Molecular Weight568.871
Flash Point273.4±26.1 °C
Exact Mass568.428040
PSA40.46000
LogP11.84
Vapour Pressure0.0±5.2 mmHg at 25°C
Index of Refraction1.585
InChIKeyJKQXZKUSFCKOGQ-QAYBQHTQSA-N
SMILESCC(C=CC=C(C)C=CC1=C(C)CC(O)CC1(C)C)=CC=CC=C(C)C=CC=C(C)C=CC1=C(C)CC(O)CC1(C)C
Storage condition−20°C

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport
WGK Germany-

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Synonyms

(3R,3'R)-Dihydroxy-b-carotene
all-trans-Zeaxanthin
EINECS 205-636-4
(1R,1'R)-4,4'-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-Tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaene-1,18-diyl]bis(3,5,5-trimethyl-3-cyclohexen-1-ol)
β,β-Carotene-3,3'-diol, (3R,3'R)-
MFCD00075654
(1R,1'R)-4,4'-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-Tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaen-1,18-diyl]bis(3,5,5-trimethyl-3-cyclohexen-1-ol)
(1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-hydroxy-2,6,6-trimethylcyclohexen-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-3-en-1-ol
(3R,3'R)-β,β-Carotene-3,3'-diol
Zeaxanthin
Zeaxanthol
Xanthophyll 3
Anchovyxanthin
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