CAS 957-68-6|7-Aminocephalosporanic acid
Introduction：Basic information about CAS 957-68-6|7-Aminocephalosporanic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 7-Aminocephalosporanic acid | ||
|---|---|---|---|
| CAS Number | 957-68-6 | Molecular Weight | 272.278 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 560.6±50.0 °C at 760 mmHg |
| Molecular Formula | C10H12N2O5S | Melting Point | >300 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 292.9±30.1 °C |
| Symbol | GHS08 | Signal Word | Danger |
Names
| Name | 7β-aminocephalosporanic acid |
|---|---|
| Synonym | More Synonyms |
7-Aminocephalosporanic acid BiologicalActivity
| Description | 7-Aminocephalosporanic acid is the core chemical structure for the synthesis of cephalosporin antibiotics, is a potent β-lactamase inhibitor. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 560.6±50.0 °C at 760 mmHg |
| Melting Point | >300 °C(lit.) |
| Molecular Formula | C10H12N2O5S |
| Molecular Weight | 272.278 |
| Flash Point | 292.9±30.1 °C |
| Exact Mass | 272.046692 |
| PSA | 135.23000 |
| LogP | -0.80 |
| Vapour Pressure | 0.0±3.3 mmHg at 25°C |
| Index of Refraction | 1.661 |
| InChIKey | HSHGZXNAXBPPDL-HZGVNTEJSA-N |
| SMILES | CC(=O)OCC1=C(C(=O)O)N2C(=O)C(N)C2SC1 |
| Storage condition | 2-8°C |
Safety Information
| Symbol | GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H317-H334 |
| Precautionary Statements | P261-P280-P342 + P311 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn,Xi |
| Risk Phrases | R42/43:May cause sensitization by inhalation and skin contact . R36/37/38:Irritating to eyes, respiratory system and skin . R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . |
| Safety Phrases | S22-S36/37-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2934996000 |
Customs
| HS Code | 2934996000 |
|---|---|
| Summary | 2934996000. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:6.0%. General tariff:20.0% |
Articles28
More Articles| Construction of recombinant Escherichia coli D11/pMSTO and its use in enzymatic preparation of 7-aminocephalosporanic acid in one pot. J. Biotechnol. 129(3) , 400-5, (2007) The main drawback in the industrial production of 7-aminocephalosporanic acid is the accumulation of intermediate (AKA-7-ACA) and destruction of substrate (cephalosporin C) catalyzed by catalase and b... | |
| Batch production of deacetyl 7-aminocephalosporanic acid by immobilized cephalosporin-C deacetylase. Appl. Microbiol. Biotechnol. 65(3) , 263-7, (2004) Bacillus subtilis SHS0133 cephalosporin-C deacetylase (CAH) overexpressed in Escherichia coli was immobilized on an anion-exchange resin, KA-890, using glutaraldehyde. The activity yield of immobilize... | |
| Site-specific protonation microequilibria of penicillin and cephalosporin beta-lactam core molecules. Eur. J. Pharm. Sci. 32(1) , 1-7, (2007) Acid-base chemistry of 6-aminopenicillanic acid (6-APA) and 7-aminocephalosporanic acid (7-ACA), the fundamental units of the two classical antibiotic families is characterised at the macroscopic and ... |
Synonyms
| 7-ACS |
| (7R)-7-Aminocephalosporanic acid |
| EINECS 213-485-0 |
| 7-AMINO CEPHALOSPORIC ACID |
| (6R,7R)-3-(Acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-amino-8-oxo-, (6R,7R)- |
| 7beta-aminocephalosporanic acid |
| 7β-aminocephalosporanic acid zwitterion |
| 3-Acetoxymethyl-7-aminoceph-3-em-4-oic Acid |
| 7β-aminocephalosporanic acid |
| 7-Amino |
| MFCD00005177 |
| 7-Aminocephalosporanicacid |
| 7-Aminocephalsporanic acid |
| 7-Aminocephalosporanic acid |
| 7-ACA |
| (6R,7R)-3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| 7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Acetate Ester |
| Cefazolin Impurity 1 |
