Introduction：Basic information about CAS 848-21-5|Norgestrienone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Norgestrienone |
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| CAS Number | 848-21-5 | Molecular Weight | 294.38700 |
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| Density | 1.21g/cm3 | Boiling Point | 498.1ºC at 760 mmHg |
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| Molecular Formula | C20H22O2 | Melting Point | 169ºC |
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| MSDS | / | Flash Point | 211.2ºC |
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Names
| Name | 17-Hydroxy-19-nor-17alpha-pregna-4,9,11-trien-20-yn-3-one |
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| Synonym | More Synonyms |
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Norgestrienone BiologicalActivity
| Description | Norgestrienone, progestin or synthetic progestin, is a progestin receptor agonist. Norgestrienone is often used as a progestational compound in birth control pills and can be used in combination with ethinyl estradiol[1]. |
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| Related Catalog | Signaling Pathways >>Others >>Progesterone ReceptorResearch Areas >>Endocrinology |
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Chemical & Physical Properties
| Density | 1.21g/cm3 |
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| Boiling Point | 498.1ºC at 760 mmHg |
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| Melting Point | 169ºC |
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| Molecular Formula | C20H22O2 |
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| Molecular Weight | 294.38700 |
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| Flash Point | 211.2ºC |
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| Exact Mass | 294.16200 |
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| PSA | 37.30000 |
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| LogP | 3.33270 |
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| Index of Refraction | 1.615 |
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| InChIKey | GVDMJXQHPUYPHP-UHFFFAOYSA-N |
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| SMILES | C#CC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C=CC21C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- RC8960080
- CHEMICAL NAME :
- 19-Nor-17-alpha-pregna-4,9,11-trien-20-yn-3-one, 17-hydroxy-
- CAS REGISTRY NUMBER :
- 848-21-5
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C20-H22-O2
- MOLECULAR WEIGHT :
- 294.42
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- DOSE :
- 1168 ug/kg
- SEX/DURATION :
- female 52 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - menstrual cycle changes or disorders Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 18,411,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- DOSE :
- 1642 ug/kg
- SEX/DURATION :
- female 52 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 18,429,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravaginal
- DOSE :
- 1 mg/kg
- SEX/DURATION :
- female 36 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 20,511,1979
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Synonyms
| Ethynyl trienolone |
| Ogyline |
