CAS 125602-71-3|(S)-Bepotastine

Introduction：Basic information about CAS 125602-71-3|(S)-Bepotastine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. (S)-Bepotastine BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	(S)-Bepotastine
CAS Number	125602-71-3	Molecular Weight	388.888
Density	1.3±0.1 g/cm3	Boiling Point	546.8±50.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₅ClN₂O₃	Melting Point	56-58 °C
MSDS	/	Flash Point	284.5±30.1 °C

Names

Name	bepotastine
Synonym	More Synonyms

(S)-Bepotastine BiologicalActivity

Description	Bepotastine is an orally active second-generation histamine H1 receptor antagonist. Bepotastine has the potential for allergic rhinitis and urticaria/pruritus treatment[1][2].
Related Catalog	Signaling Pathways >>Immunology/Inflammation >>Histamine ReceptorResearch Areas >>EndocrinologyResearch Areas >>Inflammation/ImmunologySignaling Pathways >>GPCR/G Protein >>Histamine Receptor
Target	Histamine H1 receptor[1]
References	[1]. Kanzaki S, et al. Histamine antagonist Bepotastine suppresses nasal symptoms caused by Japanese cedar and cypress pollen exposure. J Drug Assess. 2016 Sep 27;5(1):15-23. [2]. Singh DK, et al. Characterization of Photodegradation Products of Bepotastine Besilate and In silico Evaluation of Their Physicochemical, Absorption, Distribution, Metabolism, Excretion and Toxicity Properties. J Pharm Sci. 2020 Mar 12. pii: S0022-3549(20)30128-3.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	546.8±50.0 °C at 760 mmHg
Melting Point	56-58 °C
Molecular Formula	C₂₁H₂₅ClN₂O₃
Molecular Weight	388.888
Flash Point	284.5±30.1 °C
Exact Mass	388.155365
PSA	62.66000
LogP	3.67
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.605
InChIKey	YWGDOWXRIALTES-NRFANRHFSA-N
SMILES	O=C(O)CCCN1CCC(OC(c2ccc(Cl)cc2)c2ccccn2)CC1

Safety Information

Hazard Codes	Xn

Synonyms

(+)-(S)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butyric acid monobenzenesulfonate

4-[(S)-(4-chlorophenyl)-2-pyridinylMethoxy]

4-{4-[(S)-(4-Chlorophenyl)(2-pyridinyl)methoxy]-1-piperidinyl}butanoic acid

(+)-(S)-4-{4[(4-chlorphenyl)(2-pyridil)methoxy]piperidino}butyric acid monobenzenesulfonate

1-Piperidinebutanoic acid, 4-[(S)-(4-chlorophenyl)-2-pyridinylmethoxy]-

1-Piperidinebutanoic acid,4-[(S)-(4-chlorophenyl)-2-pyridinylmethoxy]

4-[4-[(4-Chlorophenyl)pyridin-2-ylmethoxy]piperidin-1-yl]butanoic acid

(+)-(S)-4-[4-[1-(4-chlorophenyl)-1-(2-pyridyl)methoxy]piperidin-1-yl]butyric acid

[14C]-Bepotastine besilate

Bepotastine

4-(4-[(1S)(4-CHLOROPHENYL)-2-PYRIDYLMETHOXY]PIPERIDYL)BUTANOIC ACID

betotastine besilate

4-(4-((S)-(4-Chlorophenyl)(pyridin-2-yl)methoxy)piperidin-1-yl)butanoic Acid

(+)-4-(((S)-p-Chloro-2-pyridylbenzyl)oxy)-1-piperidinebutyric Acid

betotastine

Bepreve

4-{4-[(S)-(4-Chlorophenyl)(pyridin-2-yl)methoxy]piperidin-1-yl}butanoic acid

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