Introduction：Basic information about CAS 129639-79-8|Abafungin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Abafungin |
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| CAS Number | 129639-79-8 | Molecular Weight | 378.491 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 533.6±52.0 °C at 760 mmHg |
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| Molecular Formula | C21H22N4OS | Melting Point | / |
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| MSDS | / | Flash Point | 276.5±30.7 °C |
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Names
| Name | abafungin |
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| Synonym | More Synonyms |
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Abafungin BiologicalActivity
| Description | Abafungin, a antifungal agent, inhibitis the transmethylation at the C-24 position of the sterol side chain, catalyzed by the enzyme sterol-C-24-methyltransferase. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Fungal |
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| References | [1]. Borelli C, Schaller M, Niewerth M, et al. Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungi. Chemotherapy. 2008;54(4):245-259. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 533.6±52.0 °C at 760 mmHg |
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| Molecular Formula | C21H22N4OS |
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| Molecular Weight | 378.491 |
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| Flash Point | 276.5±30.7 °C |
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| Exact Mass | 378.151428 |
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| PSA | 86.78000 |
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| LogP | 5.94 |
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| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
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| Index of Refraction | 1.671 |
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| InChIKey | TYBHXIFFPVFXQW-UHFFFAOYSA-N |
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| SMILES | Cc1ccc(Oc2ccccc2-c2csc(NC3=NCCCN3)n2)c(C)c1 |
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| Storage condition | 2-8°C |
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Synonyms
| N-(4-(2-((2,4-Dimethylphenyl)oxy)phenyl)-1,3-thiazol-2-yl)-1,4,5,6-tetrahydro-2-pyrimidinamine |
| 2-Pyrimidinamine, N-[4-[2-(2,4-dimethylphenoxy)phenyl]-2-thiazolyl]-1,4,5,6-tetrahydro- |
| bay w 6341 |
| Hexahydro-2-[[4-[o-(2,4-xylyloxy)phenyl]-2-thiazolyl]imino]pyrimidine |
| BAY-W 6341 |
| N-[4-[2-(2,4-Dimethylphenoxy)phenyl]-2-thiazolyl]-1,4,5,6-tetrahydro-2-pyrimidinamine |
| N-[4-[2-(2,4-dimethylphenoxy)phenyl]-1,3-thiazol-2-yl]-1,4,5,6-tetrahydropyrimidin-2-amine |
| 4-[2-(2,4-Dimethylphenoxy)phenyl]-N-(tetrahydropyrimidin-2(1H)-ylidene)-1,3-thiazol-2-amine |
| Abafungin |
| N-{4-[2-(2,4-Dimethylphenoxy)phenyl]-1,3-thiazol-2-yl}-1,4,5,6-tetrahydro-2-pyrimidinamine |
