CAS 111479-05-1|propaquizafop

Introduction：Basic information about CAS 111479-05-1|propaquizafop, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. propaquizafop BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Synonyms

Common Name	propaquizafop
CAS Number	111479-05-1	Molecular Weight	443.880
Density	1.3±0.1 g/cm3	Boiling Point	582.7±60.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₂ClN₃O₅	Melting Point	/
MSDS	ChineseUSA	Flash Point	306.2±32.9 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	propaquizafop
Synonym	More Synonyms

propaquizafop BiologicalActivity

Description	Propaquizafop is a phenoxyisopropionic acid herbicide and an acetyl-coA carboxylase inhibitor[1][2].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Metabolic Enzyme/Protease >>Acetyl-CoA Carboxylase
References	[1]. Bouis, et al. Effect of Propaquizafop and Its Free-Acid Derivative on Lauric Acid Hydroxylation and Peroxisomal Beta-Oxidation in Primary Cultured Rat, Mouse, Guinea Pig and Marmoset Hepatocytes. Toxicol In Vitro. 1993 Jul;7(4):427-31. [2]. Laura R Davies, et al. Detection and Characterization of Resistance to Acetolactate Synthase Inhibiting Herbicides in Anisantha and Bromus Species in the United Kingdom. Pest Manag Sci. 2020 Jul;76(7):2473-2482.

Description

Propaquizafop is a phenoxyisopropionic acid herbicide and an acetyl-coA carboxylase inhibitor[1][2].

Related Catalog

Research Areas >>OthersSignaling Pathways >>Metabolic Enzyme/Protease >>Acetyl-CoA Carboxylase

References

[1]. Bouis, et al. Effect of Propaquizafop and Its Free-Acid Derivative on Lauric Acid Hydroxylation and Peroxisomal Beta-Oxidation in Primary Cultured Rat, Mouse, Guinea Pig and Marmoset Hepatocytes. Toxicol In Vitro. 1993 Jul;7(4):427-31.

[2]. Laura R Davies, et al. Detection and Characterization of Resistance to Acetolactate Synthase Inhibiting Herbicides in Anisantha and Bromus Species in the United Kingdom. Pest Manag Sci. 2020 Jul;76(7):2473-2482.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	582.7±60.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₂ClN₃O₅
Molecular Weight	443.880
Flash Point	306.2±32.9 °C
Exact Mass	443.124786
PSA	92.13000
LogP	5.24
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.587
InChIKey	FROBCXTULYFHEJ-OAHLLOKOSA-N
SMILES	CC(C)=NOCCOC(=O)C(C)Oc1ccc(Oc2cnc3cc(Cl)ccc3n2)cc1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UA2458258

CHEMICAL NAME :: Propanoic acid, 2-(4-((6-chloro-2-quinoxalinyl)oxy)phenoxy)-, 2-(((1-methylethylidene)amino) oxy)ethyl ester, (R)-

CAS REGISTRY NUMBER :: 111479-05-1

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C22-H22-Cl-N3-O5

MOLECULAR WEIGHT :: 443.92

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,718,1991

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2500 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,718,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,718,1991

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H332
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn
Risk Phrases	R20
Safety Phrases	S22
RIDADR	NONH for all modes of transport

Synonyms

2-[[(1-methylethylidene)amino]oxy]ethyl (2R)-2-[4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy]propanoate

Propanoic acid,2-(4-((6-chloro-2-quinoxalinyl)oxy)phenoxy)-,2-(((1-methylethylidene)amino)oxy)ethyl ester,(R)

(R)-2-[[(1-Methylethylidene)amino]oxy]ethyl 2-[4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy]propanoate

Shogun

Propanoic acid, 2-(4-((6-chloro-2-quinoxalinyl)oxy)phenoxy)-, 2-(((1-methylethylidene)amino)oxy)ethyl ester, (R)-

Propaquizafop [ISO]

2-isopropylideneaminooxyethyl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenoxy]propionate

2-[(Isopropylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate

propaquizafop

2-[(Propan-2-ylidenamino)oxy]ethyl-(2R)-2-{4-[(6-chlorchinoxalin-2-yl)oxy]phenoxy}propanoat

2-Isopropylideneamino-oxyethyl (R)-2-(4-(6-chloroquinoxalin-2-yloxy)phenoxy)propionate

Ro 17-3664

2-{[(propan-2-ylidene)amino]oxy}ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate

2-Isopropylideneamino-oxyethyl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenoxy]propionate

2-[(Isopropylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy}propanoate

Propanoic acid, 2-[4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy]-, 2-[[(1-methylethylidene)amino]oxy]ethyl ester, (2R)-

2-(propan-2-ylideneamino)oxyethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate

AGIL

2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate

2-[(2-Propanylidenamino)oxy]ethyl-(2R)-2-{4-[(6-chlor-2-chinoxalinyl)oxy]phenoxy}propanoat

(2R)-2-{4-[(6-Chloro-2-quinoxalinyl)oxy]phénoxy}propanoate de 2-[(isopropylidéneamino)oxy]éthyle

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