CAS 515-64-0|sulfisomidine
Introduction：Basic information about CAS 515-64-0|sulfisomidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | sulfisomidine | ||
|---|---|---|---|
| CAS Number | 515-64-0 | Molecular Weight | 278.330 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 480.7±55.0 °C at 760 mmHg |
| Molecular Formula | C12H14N4O2S | Melting Point | 245ºC |
| MSDS | ChineseUSA | Flash Point | 244.5±31.5 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | sulfisomidine |
|---|---|
| Synonym | More Synonyms |
sulfisomidine BiologicalActivity
| Description | Sulfisomidin is a sulfonamide antibacterial. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection |
| In Vitro | Sulfisomidin (Sulfaisodimidine) is a short-acting antibacterial agent[1]. |
| References | [1]. Bridges JW, et al. Species differences in the metabolism and excretion of sulphasomidine andsulphamethomidine. Biochem J. 1969 Jan;111(2):173-9. |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 480.7±55.0 °C at 760 mmHg |
| Melting Point | 245ºC |
| Molecular Formula | C12H14N4O2S |
| Molecular Weight | 278.330 |
| Flash Point | 244.5±31.5 °C |
| Exact Mass | 278.083740 |
| PSA | 106.35000 |
| LogP | -0.43 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.644 |
| InChIKey | YZMCKZRAOLZXAZ-UHFFFAOYSA-N |
| SMILES | Cc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(C)n1 |
| Storage condition | 0-6°C |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 94,338,1953 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 6 gm/kg
- SEX/DURATION :
- female 9-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- REFERENCE :
- SEIJBO Senten Ijo. Congenital Anomalies. (Nippon Senten Ijo Gakkai, c/o Kinki Daigaku Igakubu Kaibagaku Kyoshitsu, 380 Nishiyama, Sayama-cho, Mirami-Kawachi-gun, Osaka-fu, Japan) V.1-26, 1960-86. For publisher information, see CGANE7. Volume(issue)/page/year: 13,7,1973
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- DOSE :
- 2500 mg/kg
- SEX/DURATION :
- female 8-12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- REFERENCE :
- AKGIAO Akushcherstvo i Ginekologiya (Moscow). (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1936- Volume(issue)/page/year: 43(12),10,1967
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | S26;S36 |
| RIDADR | UN 3249 |
| RTECS | WO9270000 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
| HS Code | 2935009090 |
Customs
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
Articles27
More Articles| Fast determination of 22 sulfonamides from chicken breast muscle using core-shell nanoring amino-functionalized superparamagnetic molecularly imprinted polymer followed by liquid chromatography-tandem mass spectrometry. J. Chromatogr. A. 1345 , 17-28, (2014) A novel, simple and sensitive method was developed for the simultaneous determination of 22 sulfonamides (SAs) in chicken breast muscle by using the dispersive micro-solid-phase extraction (d-μ-SPE) p... | |
| Multiresidue analysis of sulfonamides, quinolones, and tetracyclines in animal tissues by ultra-high performance liquid chromatography-tandem mass spectrometry. Food Chem. 204 , 252-62, (2016) A multiresidue method for the efficient identification and quantification of 38 compounds from 3 different classes of antibiotics (tetracyclines, sulfonamides, and quinolones) in animal tissues has be... | |
| Coulometric determination of sulphisomidine, sulphamethoxydiazine and sulphamoxole. J. Pharm. Biomed. Anal. 9(2) , 199-201, (1991) |
Synonyms
| Solfisomidina |
| 4-amino-N-(2,6-dimethyl-pyrimidin-4-yl)-benzenesulfonamide |
| Sulfaisodimidinum |
| 4-amino-N-(2,6-dimethyl-4-pyrimidinyl)benzenesulfonamide |
| Sulfaisodimidine |
| Sulfisomidin |
| Sulfaisomidine |
| 6-(Sulfanilamido)-2,4-dimethyl-1,3-diazine |
| sulfisomidine |
| Sulfadimetine |
| benzenesulfonamide, 4-amino-N-(2,6-dimethyl-4-pyrimidinyl)- |
| Sulfuisodimidine |
| Sulphasomidine |
| Sulfasomidine |
| MFCD00010567 |
| 4-Amino-N-(2,6-dimethylpyrimidin-4-yl)benzenesulfonamide |
| Sulfudimetine |
| EINECS 208-204-3 |
| Sulfamethin |
| 2,6-dimethyl-4-pyrimidinyl sulphanilamide |
| 6-(p-Aminophenylsulfonamido)-2,4-dimethylpyrimidine |
| Domain |
