Introduction：Basic information about CAS 35597-43-4|bilanafos, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | bilanafos |
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| CAS Number | 35597-43-4 | Molecular Weight | 323.28300 |
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| Density | 1.33g/cm3 | Boiling Point | 793.2ºC at 760 mmHg |
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| Molecular Formula | C11H22N3O6P | Melting Point | 159-161ºC |
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| MSDS | / | Flash Point | 433.5ºC |
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Names
| Name | bilanafos |
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| Synonym | More Synonyms |
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bilanafos BiologicalActivity
| Description | Bilanafos is a natural organic phosphine tripeptide antibiotic metabolized by Streptomyces hydroscopius or Streptomyces viridochromeogenes. Bialaphos has antimicrobial activity aganist Gram-negative and positive bacteria as well as some fungal plant diseases[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. Takeshi Murakami, et al.The bialaphos biosynthetic genes ofStreptomyces hygroscopicus: Molecular cloning and characterization of the gene cluster. Molecular and General Genetics MGG volume 205, pages42–53 (1986) |
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Chemical & Physical Properties
| Density | 1.33g/cm3 |
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| Boiling Point | 793.2ºC at 760 mmHg |
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| Melting Point | 159-161ºC |
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| Molecular Formula | C11H22N3O6P |
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| Molecular Weight | 323.28300 |
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| Flash Point | 433.5ºC |
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| Exact Mass | 323.12500 |
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| PSA | 182.29000 |
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| Index of Refraction | 1.517 |
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| InChIKey | GINJFDRNADDBIN-FXQIFTODSA-N |
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| SMILES | CC(NC(=O)C(C)NC(=O)C(N)CCP(C)(=O)O)C(=O)O |
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| Storage condition | Store dry at -4 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- AY6826000
- CHEMICAL NAME :
- L-Alanine, gamma-(hydroxymethylphosphinyl)-L-alpha-aminobutyryl- L-alanyl-
- CAS REGISTRY NUMBER :
- 35597-43-4
- LAST UPDATED :
- 199604
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C11-H22-N3-O6-P
- MOLECULAR WEIGHT :
- 323.33
- WISWESSER LINE NOTATION :
- QVY1&MVY1&MVYZ2PHO&1Q
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),223,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),223,1980
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Safety Information
| Hazard Codes | Xn |
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| Risk Phrases | R20/21/22 |
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| Safety Phrases | 26-36 |
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Synonyms
| (2S)-2-amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl-L-alanine |
| bialaphos |
| (2S)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyryl-L-alanyl-L-alanine |
| Bilanafos [ISO] |
| L-Alanine,4-(hydroxymethylphosphinyl)-L-2-aminobutanoyl-L-alanyl |
| acide diprogulique |
| Bialaphos |
| Antibiotic SF 1293 |
| Phosphinothricylalanylalanine |
| Bilanafos |
| (2S)-2-[[(2S)-2-[[(2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoyl]amino]propanoyl]amino]propanoic acid |
