CAS 75-91-2|tert-Butyl Hydroperoxide
Introduction：Basic information about CAS 75-91-2|tert-Butyl Hydroperoxide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | tert-Butyl Hydroperoxide | ||
|---|---|---|---|
| CAS Number | 75-91-2 | Molecular Weight | 90.121 |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 120.4±9.0 °C at 760 mmHg |
| Molecular Formula | C4H10O2 | Melting Point | -2.8 °C |
| MSDS | ChineseUSA | Flash Point | 35.0±0.0 °C |
| Symbol | GHS02, GHS05, GHS06, GHS08, GHS09 | Signal Word | Danger |
Names
| Name | tert-butyl hydroperoxide |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 120.4±9.0 °C at 760 mmHg |
| Melting Point | -2.8 °C |
| Molecular Formula | C4H10O2 |
| Molecular Weight | 90.121 |
| Flash Point | 35.0±0.0 °C |
| Exact Mass | 90.068077 |
| PSA | 29.46000 |
| LogP | 1.38 |
| Vapour Pressure | 7.4±0.5 mmHg at 25°C |
| Index of Refraction | 1.399 |
| InChIKey | CIHOLLKRGTVIJN-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OO |
| Stability | Stable, but may explode if heated under confinement. Decomposition may be accelerated by traces of metals, molecular sieve or other contaminants. Incompatible with reducing agents, combustible material, acids. |
| Water Solubility | Miscible |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Rinsed with water
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 370 mg/kg
- TOXIC EFFECTS :
- Behavioral - irritability Gastrointestinal - alteration in gastric secretion Blood - hemorrhage
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 ppm/4H
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 790 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 87 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 320 mg/kg
- TOXIC EFFECTS :
- Behavioral - irritability Gastrointestinal - alteration in gastric secretion Blood - hemorrhage
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 350 ppm/4H
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 246 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 460 uL/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - cyanosis Liver - other changes Kidney, Ureter, Bladder - other changes in urine composition
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 107 mg/m3/17W-I
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Olfaction) - change in sensation of smell Kidney, Ureter, Bladder - other changes in urine composition Nutritional and Gross Metabolic - changes in chlorine
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 365 mg/kg/7W-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 107 mg/m3/17W-I
- TOXIC EFFECTS :
- Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Dominant lethal test
MUTATION DATA - TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 34 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 182,135,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-GERMANY JAN 1993 OEL-RUSSIA:STEL 5 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 14730 No. of Facilities: 75 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 433 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 14730 No. of Facilities: 266 (estimated) No. of Industries: 8 No. of Occupations: 14 No. of Employees: 12168 (estimated) No. of Female Employees: 4787 (estimated)
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 34 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 182,135,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-GERMANY JAN 1993 OEL-RUSSIA:STEL 5 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 14730 No. of Facilities: 75 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 433 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 14730 No. of Facilities: 266 (estimated) No. of Industries: 8 No. of Occupations: 14 No. of Employees: 12168 (estimated) No. of Female Employees: 4787 (estimated)
Safety Information
| Symbol | GHS02, GHS05, GHS06, GHS08, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H226-H242-H302-H304-H311 + H331-H314-H317-H336-H341-H410 |
| Precautionary Statements | P210-P234-P280-P301 + P310-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P331-P403 + P233 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | C:Corrosive |
| Risk Phrases | R10;R20/21/22;R34;R43;R52/53;R7 |
| Safety Phrases | S14-S3/7-S61-S45-S36/37/39-S24-S17-S16-S14A-S26-S62 |
| RIDADR | UN 3109 5.2 |
| WGK Germany | 3 |
| RTECS | EQ4900000 |
| Packaging Group | II |
| Hazard Class | 5.2 |
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Synonyms
| 2-hydroperoxy-2-methylpropane |
| MFCD00002130 |
| EINECS 200-915-7 |
| tert-Butyl hydroperoxide |
