CAS 143-74-8|Phenol red
Introduction：Basic information about CAS 143-74-8|Phenol red, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Phenol red | ||
|---|---|---|---|
| CAS Number | 143-74-8 | Molecular Weight | 354.376 |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 562.8±50.0 °C at 760 mmHg |
| Molecular Formula | C19H14O5S | Melting Point | 300 °C |
| MSDS | ChineseUSA | Flash Point | 294.2±30.1 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | Phenol red |
|---|---|
| Synonym | More Synonyms |
Phenol red BiologicalActivity
| Description | Phenol red (Phenolsulfonephthalein) is a pH indicator dye, relying on a distinct color change from pink to yellow in case of a positive reaction[1] [2]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| In Vitro | Phenol red (PR) is the standard pH indicator in various cell and tissue culture media, as it provides a quick check for the health of the culture. Phenol red has also been used in multiple protocols to detect cellular hydrogen peroxide as well as peroxidase activity from human peroxidase enzymes[1]. |
| References | [1]. Morgan A, et al. Caution for the routine use of phenol red - It is more than just a pH indicator. Chem Biol Interact. 2019;310:108739. [2]. Peltzer D, et al. Rapid and simple colorimetric loop-mediated isothermal amplification (LAMP) assay for the detection of Bovine alphaherpesvirus 1. J Virol Methods. 2021;289:114041. |
Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 562.8±50.0 °C at 760 mmHg |
| Melting Point | 300 °C |
| Molecular Formula | C19H14O5S |
| Molecular Weight | 354.376 |
| Flash Point | 294.2±30.1 °C |
| Exact Mass | 354.056183 |
| PSA | 92.21000 |
| LogP | 3.02 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.697 |
| InChIKey | BELBBZDIHDAJOR-UHFFFAOYSA-N |
| SMILES | O=S1(=O)OC(c2ccc(O)cc2)(c2ccc(O)cc2)c2ccccc21 |
| Storage condition | Store at RT. |
| Water Solubility | 0.77 g/L |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 752 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1368 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 1 mg/plate
- REFERENCE :
- AEMIDF Applied and Environmental Microbiology. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.31- 1976- Volume(issue)/page/year: 42,641,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82224 No. of Facilities: 1719 (estimated) No. of Industries: 16 No. of Occupations: 13 No. of Employees: 5387 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82224 No. of Facilities: 2166 (estimated) No. of Industries: 19 No. of Occupations: 26 No. of Employees: 27087 (estimated) No. of Female Employees: 14345 (estimated)
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 1 mg/plate
- REFERENCE :
- AEMIDF Applied and Environmental Microbiology. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.31- 1976- Volume(issue)/page/year: 42,641,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82224 No. of Facilities: 1719 (estimated) No. of Industries: 16 No. of Occupations: 13 No. of Employees: 5387 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82224 No. of Facilities: 2166 (estimated) No. of Industries: 19 No. of Occupations: 26 No. of Employees: 27087 (estimated) No. of Female Employees: 14345 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S37/39-S26 |
| RIDADR | NONH for all modes of transport |
| RTECS | SJ7490000 |
| Packaging Group | I; II; III |
| HS Code | 29349990 |
Customs
| HS Code | 2934991000 |
|---|---|
| Summary | 2934991000. sultones and sultams. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| 3,3-bis(p-hydroxyphenyl)-3h-2,1-benzoxathiole 1,1-dioxide |
| Phenolsulfonphthalein |
| P.S.P. |
| a-Hydroxy-a,a-bis(p-hydroxyphenyl)-o-toluenesulfonic Acid g-Sultone |
| PSP |
| EINECS 205-609-7 |
| TF-R 2 |
| 4-[3-(4-hydroxyphenyl)-1,1-dioxo-2,1λ<sup>6</sup>-benzoxathiol-3-yl]phenol |
| 4,4'-(1,1-Dioxido-3H-2,1-benzoxathiole-3,3-diyl)diphenol |
| 4,4'-(3H-2,1-Benzoxathiol-3-ylidene)bisphenol S,S-Dioxide |
| Phenol, 4,4'-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis- |
| Phenol red |
| MFCD00003552 |
