CAS 70-55-3|4-Toluenesulfonamide
Introduction：Basic information about CAS 70-55-3|4-Toluenesulfonamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-Toluenesulfonamide | ||
|---|---|---|---|
| CAS Number | 70-55-3 | Molecular Weight | 171.22 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 322.2±35.0 °C at 760 mmHg |
| Molecular Formula | C7H9NO2S | Melting Point | 134-137 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 148.6±25.9 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | toluene-4-sulfonamide |
|---|---|
| Synonym | More Synonyms |
4-Toluenesulfonamide BiologicalActivity
| Description | p-Toluenesulfonamide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 322.2±35.0 °C at 760 mmHg |
| Melting Point | 134-137 °C(lit.) |
| Molecular Formula | C7H9NO2S |
| Molecular Weight | 171.22 |
| Flash Point | 148.6±25.9 °C |
| Exact Mass | 171.035400 |
| PSA | 68.54000 |
| LogP | 0.79 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.564 |
| InChIKey | LMYRWZFENFIFIT-UHFFFAOYSA-N |
| SMILES | Cc1ccc(S(N)(=O)=O)cc1 |
| Water Solubility | 0.32 g/100 mL (25 º C) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - excitement Behavioral - muscle weakness
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - wild bird species
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TEST SYSTEM :
- Insect - Drosophila melanogaster
- DOSE/DURATION :
- 2500 umol/plate
- REFERENCE :
- 45OHAA "Short-Term Test Systems for Detecting Carcinogens, Proceedings of the Symposium, 1978," Norpoth, K.H., and R.G. Garner, eds., Berlin, Springer-Verlag, 1980 Volume(issue)/page/year: -,170,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1329 No. of Facilities: 195 (estimated) No. of Industries: 5 No. of Occupations: 29 No. of Employees: 4613 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1329 No. of Facilities: 304 (estimated) No. of Industries: 8 No. of Occupations: 16 No. of Employees: 9023 (estimated) No. of Female Employees: 1223 (estimated)
- TEST SYSTEM :
- Insect - Drosophila melanogaster
- DOSE/DURATION :
- 2500 umol/plate
- REFERENCE :
- 45OHAA "Short-Term Test Systems for Detecting Carcinogens, Proceedings of the Symposium, 1978," Norpoth, K.H., and R.G. Garner, eds., Berlin, Springer-Verlag, 1980 Volume(issue)/page/year: -,170,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1329 No. of Facilities: 195 (estimated) No. of Industries: 5 No. of Occupations: 29 No. of Employees: 4613 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1329 No. of Facilities: 304 (estimated) No. of Industries: 8 No. of Occupations: 16 No. of Employees: 9023 (estimated) No. of Female Employees: 1223 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| RTECS | XT5075000 |
| Packaging Group | III |
| HS Code | 2935009090 |
Customs
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
Articles56
More Articles| Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata. Bioorg. Med. Chem. Lett. 21 , 710-4, (2011) The catalytic activity and the inhibition of a new coral carbonic anhydrase (CA, EC 4.2.1.1), from the scleractinian coral Stylophora pistillata, STPCA-2, has been investigated. STPCA-2 has high catal... | |
| Identifying chelators for metalloprotein inhibitors using a fragment-based approach. J. Med. Chem. 54 , 591-602, (2011) Fragment-based lead design (FBLD) has been used to identify new metal-binding groups for metalloenzyme inhibitors. When screened at 1 mM, a chelator fragment library (CFL-1.1) of 96 compounds produced... | |
| Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana. Bioorg. Med. Chem. 20 , 1403-10, (2012) The α-carbonic anhydrase (CA, EC 4.2.1.1) Astrosclerin-3 previously isolated from the living fossil sponge Astrosclera willeyana (Jackson et al., Science 2007, 316, 1893), was cloned, kinetically char... |
Synonyms
| 4-Methylbenzenesulfonamide |
| 4-Toluenesulfonamide |
| p-Toluenesulfonamide |
| MFCD00011692 |
| Benzenesulfonamide, 4-methyl- |
| ZSWR D1 |
| EINECS 200-741-1 |
| p-Tosylamide |
