Introduction：Basic information about CAS 68858-21-9|4-(Hydroxymethyl)phenoxyacetic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-(Hydroxymethyl)phenoxyacetic acid |
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| CAS Number | 68858-21-9 | Molecular Weight | 182.173 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 378.3±22.0 °C at 760 mmHg |
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| Molecular Formula | C9H10O4 | Melting Point | 112-114 °C |
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| MSDS | ChineseUSA | Flash Point | 156.3±15.8 °C |
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Names
| Name | 4-(Hydroxymethyl)phenoxyacetic acid |
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| Synonym | More Synonyms |
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4-(Hydroxymethyl)phenoxyacetic acid BiologicalActivity
| Description | 4-(Hydroxymethyl)phenoxyacetic acid is an acid-labile resin linkage agent for use in solid phase peptide synthesis[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. C T Bui, et al. Improving the performance of an acid-labile 4-hydroxymethyl phenoxyacetic acid (HMP) linker on resin and SynPhase grafted solid-supports. J Pept Sci. 2000 Oct;6(10):534-8. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 378.3±22.0 °C at 760 mmHg |
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| Melting Point | 112-114 °C |
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| Molecular Formula | C9H10O4 |
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| Molecular Weight | 182.173 |
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| Flash Point | 156.3±15.8 °C |
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| Exact Mass | 182.057907 |
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| PSA | 66.76000 |
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| LogP | 0.16 |
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| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
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| Index of Refraction | 1.573 |
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| InChIKey | VUCNQOPCYRJCGQ-UHFFFAOYSA-N |
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| SMILES | O=C(O)COc1ccc(CO)cc1 |
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| Storage condition | 2-8°C |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S22-S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| HS Code | 2918990090 |
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Customs
| HS Code | 2918990090 |
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| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Articles5
More Articles
| Acid-labile resin linkage agents for use in solid phase peptide synthesis. Int. J. Pept. Protein Res. 20(5) , 451-4, (1982) Details are given of the preparation of two acid-labile peptide-resin linkage agents for use in solid phase peptide synthesis, viz. 4-hydroxymethylphenoxy-acetic acid and 3-methoxy-4-hydroxymethylphen... | |
| Improving the performance of an acid-labile 4-hydroxymethyl phenoxyacetic acid (HMP) linker on resin and SynPhase grafted solid-supports. J. Pept. Sci. 6(10) , 534-8, (2000) A replacement of the acetic acid moiety by valeric acid within the 4-hydroxymethylphenoxyacetic acid (HMP) linker (Sheppard RC, Williams BJ. Acid-labile resin linkage agents for use in solid phase pep... | |
| E. Atherton et al. J. Chem. Soc. Chem. Commun. , 537, (1978)
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Synonyms
| HMP Linker |
| Acetic acid, 2-[4-(hydroxymethyl)phenoxy]- |
| HMPLinker |
| 2-[4-(hydroxymethyl)phenoxy]acetic acid |
| [4-(Hydroxymethyl)phenoxy]acetic acid |
| MFCD00057827 |
| EINECS 229-560-6 |
| HMP-Linker |
