CAS 120068-37-3|Fipronil
Introduction：Basic information about CAS 120068-37-3|Fipronil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fipronil | ||
|---|---|---|---|
| CAS Number | 120068-37-3 | Molecular Weight | 437.148 |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 510.1±50.0 °C at 760 mmHg |
| Molecular Formula | C12H4Cl2F6N4OS | Melting Point | 200-201°C |
| MSDS | ChineseUSA | Flash Point | 262.3±30.1 °C |
| Symbol | GHS06, GHS08, GHS09 | Signal Word | Danger |
Names
| Name | fipronil |
|---|---|
| Synonym | More Synonyms |
Fipronil BiologicalActivity
| Description | Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC500s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes. |
|---|---|
| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>Cytochrome P450Signaling Pathways >>Membrane Transporter/Ion Channel >>GABA ReceptorSignaling Pathways >>Neuronal Signaling >>GABA Receptor |
Chemical & Physical Properties
| Density | 1.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 510.1±50.0 °C at 760 mmHg |
| Melting Point | 200-201°C |
| Molecular Formula | C12H4Cl2F6N4OS |
| Molecular Weight | 437.148 |
| Flash Point | 262.3±30.1 °C |
| Exact Mass | 435.938690 |
| PSA | 103.91000 |
| LogP | 4.76 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.618 |
| InChIKey | ZOCSXAVNDGMNBV-UHFFFAOYSA-N |
| SMILES | N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1S(=O)C(F)(F)F |
| Storage condition | 0-6°C |
Safety Information
| Symbol | GHS06, GHS08, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 + H311 + H331-H319-H372-H410 |
| Precautionary Statements | P261-P273-P280-P301 + P310 + P330-P302 + P352 + P312-P304 + P340 + P312 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| Hazard Codes | N: Dangerous for the environment;T: Toxic; |
| Risk Phrases | R23/24/25 |
| Safety Phrases | S26-S36/37/39-S45-S60-S61 |
| RIDADR | 2588 |
| WGK Germany | 3.0 |
| RTECS | UQ4430250 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
Articles27
More Articles| Superficially porous particles vs. fully porous particles for bonded high performance liquid chromatographic chiral stationary phases: isopropyl cyclofructan 6. J. Chromatogr. A. 1363 , 89-95, (2014) This work reports a comparison of HPLC separations of enantiomers with chiral stationary phases (CSPs) prepared by chemically bonding cyclofructan-6, functionalized with isopropyl carbamate groups on ... | |
| Persistence and effect of processing on reduction of fipronil and its metabolites in chilli pepper (Capsicum annum L.) fruits. Environ. Monit. Assess. 186(9) , 5429-37, (2014) A single laboratory UPLC-MS/MS method was developed and validated for the estimation of fipronil and its metabolites in fresh and dry chilli pepper fruits. Dissipation of fipronil on chilli fruits was... | |
| Acute toxicity and sublethal effects of fipronil on detoxification enzymes in juvenile zebrafish (Danio rerio) Pestic. Biochem. Physiol. 115 , 9-14, (2014) The acute toxicity of fipronil and its sublethal effects on detoxification enzymes (carboxylesterases (CarEs), glutathione S-transferases (GSTs), and 7-ethoxycoumarin O-deethylase (ECOD)) in zebrafish... |
Synonyms
| Fipronil (JAN) |
| 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl)pyrazole-3-carbonitrile |
| 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carbonitrile |
| Fluocyanobenpyrazole |
| EINECS 424-610-5 |
| 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile |
| 1H-Pyrazole-3-carbonitrile, 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]- |
| 5-Amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfinylpyrazole |
| (±)-Fipronil |
| 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)sulfinyl-1H-pyrazole-3-carbonitrile |
| (±)-5-Amino-1-(2,6-dichloro-a,a,a-trifluoro-p-tolyl)-4-trifluoromethylsulfinylpyrazole-3-carbonitrile |
| RM 1601 |
| MFCD00867812 |
| Termidor |
| T5NNJ AR BG FG DXFFF& CCN DSO&XFFF EZ &&(RS) Form |
| 5-Amino-1-(2,6-dichloro-α,α,α-trifluoro-p-tolyl)-4-[(trifluoromethyl)sulfinyl]pyrazole-3-carbonitrile |
| Fipronil |
