Introduction：Basic information about CAS 194920-62-2|N-Boc-C1-PEG3-C3-NH2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-Boc-C1-PEG3-C3-NH2 |
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| CAS Number | 194920-62-2 | Molecular Weight | 320.425 |
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| Density | 1.0±0.1 g/cm3 | Boiling Point | 432.4±35.0 °C at 760 mmHg |
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| Molecular Formula | C15H32N2O5 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 215.3±25.9 °C |
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Names
| Name | tert-butyl N-[3-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]propyl]carbamate |
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| Synonym | More Synonyms |
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N-Boc-C1-PEG3-C3-NH2 BiologicalActivity
| Description | N-Boc-C1-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
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| Boiling Point | 432.4±35.0 °C at 760 mmHg |
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| Molecular Formula | C15H32N2O5 |
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| Molecular Weight | 320.425 |
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| Flash Point | 215.3±25.9 °C |
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| Exact Mass | 320.231110 |
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| PSA | 92.04000 |
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| LogP | 0.27 |
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| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
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| Index of Refraction | 1.463 |
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| InChIKey | WHHYAYNALHPDGJ-UHFFFAOYSA-N |
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| SMILES | CC(C)(C)OC(=O)NCCCOCCOCCOCCCN |
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| Storage condition | 2-8°C |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves |
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| Hazard Codes | Xi |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| HS Code | 2924199090 |
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Customs
| HS Code | 2924199090 |
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| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Articles1
More Articles
| Erkang, F., et al. J. Am. Chem. Soc. 122 , 2663 - 2664, (2000)
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Synonyms
| N-Boc-trioxatridecanediamine |
| 2-Methyl-2-propanyl (3-{2-[2-(3-aminopropoxy)ethoxy]ethoxy}propyl)carbamate |
| H2N-TEG-NHBoc |
| tert-Butyl (3-(2-(2-(3-aminopropoxy)ethoxy)ethoxy)propyl)carbamate |
| N-Boc-4,7,10-trioxa-1,13-tridecanediamine |
| Carbamic acid, N-[3-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]propyl]-, 1,1-dimethylethyl ester |
| AmbotzBNN1028 |
| Boc-TOTA |
