CAS 75-62-7|Bromotrichloromethane
Introduction：Basic information about CAS 75-62-7|Bromotrichloromethane, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Bromotrichloromethane | ||
|---|---|---|---|
| CAS Number | 75-62-7 | Molecular Weight | 198.27400 |
| Density | 2.012 g/mL at 25 °C(lit.) | Boiling Point | 105 °C(lit.) |
| Molecular Formula | CBrCl3 | Melting Point | −6 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 104-105°C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | Bromotrichloromethane |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 2.012 g/mL at 25 °C(lit.) |
|---|---|
| Boiling Point | 105 °C(lit.) |
| Melting Point | −6 °C(lit.) |
| Molecular Formula | CBrCl3 |
| Molecular Weight | 198.27400 |
| Flash Point | 104-105°C |
| Exact Mass | 195.82500 |
| LogP | 2.70900 |
| Vapour density | 6.85 (vs air) |
| Vapour Pressure | 38.4 mm Hg ( 25 °C) |
| Index of Refraction | n20/D 1.5065(lit.) |
| InChIKey | XNNQFQFUQLJSQT-UHFFFAOYSA-N |
| SMILES | ClC(Cl)(Cl)Br |
| Water Solubility | insoluble |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 119 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
MUTATION DATA - TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 1 mmol/L
- REFERENCE :
- TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 11,243,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1152 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 34 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1152 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)
- TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 1 mmol/L
- REFERENCE :
- TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 11,243,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1152 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 34 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1152 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 + H312 + H332 |
| Precautionary Statements | P280 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R20/21/22;R36/37/38 |
| Safety Phrases | S36/37-S36/37/39-S26 |
| RIDADR | UN 2810 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | PA5400000 |
| Packaging Group | III |
| Hazard Class | 6.1 |
| HS Code | 29034700 |
Customs
| HS Code | 29034700 |
|---|
Articles28
More Articles| Increased proteolysis after single-dose exposure with hepatotoxins in HepG2 cells. Free Radic. Biol. Med. 33(2) , 283-91, (2002) Chronic ethanol consumption is associated with increased protein oxidation and decreased proteolysis in the liver. We tested the hypothesis that even single-dose treatment with ethanol or bromotrichlo... | |
| Suicidal inactivation of haemoproteins by reductive metabolites of halomethanes: a structure-activity relationship study. Toxicology 100(1-3) , 175-83, (1995) Human haemoglobin (Hb), methaemalbumin (MHA) or rat liver microsomal cytochrome P-450 (P-450) were incubated anaerobically at microM concentrations with 1 mM carbon tetrachloride (CCl4), trichlorobrom... | |
| Use of rat liver slices for the study of oxidative DNA damage in comparison with isolated rat liver nuclei and HepG2 human hepatoma cells. Food Chem. Toxicol. 38(5) , 451-8, (2000) Tissue slices are a useful biological system for lipid peroxidation studies but their use for DNA damage studies is not well characterized. Hence, the present study investigates DNA damage in rat live... |
Synonyms
| bromo(trichloro)methane |
| MFCD00000783 |
| EINECS 200-886-0 |
