CAS 124012-42-6|N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]

Introduction：Basic information about CAS 124012-42-6|N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl], including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Synonyms

Common Name	N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]-3,4,5-trimethoxybenzamide
CAS Number	124012-42-6	Molecular Weight	439.39200
Density	/	Boiling Point	/
Molecular Formula	C₁₉H₂₂FN₃O₈	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]-3,4,5-trimethoxybenzamide
Synonym	More Synonyms

Chemical & Physical Properties

Molecular Formula	C₁₉H₂₂FN₃O₈
Molecular Weight	439.39200
Exact Mass	439.13900
PSA	141.37000
LogP	0.37260
InChIKey	TVYPSLDUBVTDIS-FUOMVGGVSA-N
SMILES	COc1cc(C(=O)Nc2nc(=O)n(C3OC(C)C(O)C3O)cc2F)cc(OC)c1OC

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HA3857500

CHEMICAL NAME :: Cytidine, 5'-deoxy-5-fluoro-N-(3,4,5-trimethoxybenzoyl)-

CAS REGISTRY NUMBER :: 124012-42-6

LAST UPDATED :: 199703

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C19-H22-F-N3-O8

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6300 mg/kg/7D-I

TOXIC EFFECTS :: Endocrine - changes in thymus weight Blood - changes in bone marrow (not otherwise specified) Blood - changes in leukocyte (WBC) count

REFERENCE :: JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 21,29,1996

Synonyms

Galocitabinum [INN-Latin]

Cytidine,5'-deoxy-5-fluoro-N-(3,4,5-trimethoxybenzoyl)

Galocitabine [INN]

5'-deoxy-5-fluoro-N4-(3,4,5-trimethoxybenzoyl)cytidine

5'-Deoxy-5-fluoro-N-(3,4,5-trimethoxybenzoyl)cytidine

N4-Trimethoxybenzoyl-5'-deoxy-5-fluorocytidine

Galocitabina [INN-Spanish]

galocitabine

Ro-09-1390

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