CAS 3818-50-6|Bephenium (hydroxynaphthoate)
| Common Name | Bephenium (hydroxynaphthoate) | ||
|---|---|---|---|
| CAS Number | 3818-50-6 | Molecular Weight | 443.53400 |
| Density | / | Boiling Point | / |
| Molecular Formula | C28H29NO4 | Melting Point | 170-171ºC |
| MSDS | ChineseUSA | Flash Point | / |
Names
| Name | benzyl-dimethyl-(2-phenoxyethyl)azanium,3-carboxynaphthalen-2-olate |
|---|---|
| Synonym | More Synonyms |
Bephenium (hydroxynaphthoate) BiologicalActivity
| Description | Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B-type AChR activator. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>ParasiteResearch Areas >>Infection |
| References | [1]. JAYEWARDENE G, et al. Bephenium hydroxynaphthoate in treatment of ascariasis. Br Med J. 1960 Jul 23;2(5194):268-71. [2]. Charvet CL, et al. Selective effect of the anthelmintic bephenium on Haemonchus contortus levamisole-sensitive acetylcholine receptors. Invert Neurosci. 2012 Jun;12(1):43-51. |
Chemical & Physical Properties
| Melting Point | 170-171ºC |
|---|---|
| Molecular Formula | C28H29NO4 |
| Molecular Weight | 443.53400 |
| Exact Mass | 443.21000 |
| PSA | 69.59000 |
| LogP | 4.25090 |
| InChIKey | PMPQCPQAHTXCDK-UHFFFAOYSA-M |
| SMILES | C[N+](C)(CCOc1ccccc1)Cc1ccccc1.O=C(O)c1cc2ccccc2cc1[O-] |
| Storage condition | 2-8℃ |
Safety Information
| RIDADR | NONH for all modes of transport |
|---|---|
| WGK Germany | 3 |
Articles9
More Articles| Use of common salt fortified with iron in the control and prevention of anemia--a collaborative study. Report of the Working Group on Fortification of Salt with Iron. Am. J. Clin. Nutr. 35(6) , 1442-51, (1982) The efficacy of salt fortified with iron (FePO4 and NaHSO4) to control anemia was investigated by large scale field trials in three rural areas and one urban area located in different parts of India, ... | |
| Controlled comparative study of the efficacy of pyrantel pamoate and a combined regimen of piperazine citrate and bephenium hydroxynaphthoate in the treatment of intestinal nemathelminthiases. Afr. J. Med. Med. Sci. 10(1-2) , 63-7, (1981) Pyrantel pamoate at a dose of 10 mg/kg body weight daily for 2 or 3 days was found to be more effective against Ascaris than both a regimen of bephenium hydroxynaphthoate (2.5 g base) and piperazine c... | |
| [Hookworm control by combining drug treatment with biogas production]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 5(1) , 58-60, (1987) |
Synonyms
| Naphthammon |
| Hidroxinaftoato de befenio |
| BepheniumHydroxynapthoate |
| Befenium |
| BEPHENIUM HYDROXYNAPHTHOATE |
| Naphthammonum |
| Alcopar |
| Bephenii hydroxynaphthoas |
| Bephenium Hydroxynapthoate |
| Hydorxynaphtoate de bephenium |
| Naphthamone |
| Bephenium (hydroxynaphthoate) |
