CAS 147221-93-0|DELAVIRDINE MESYLATE
| Common Name | DELAVIRDINE MESYLATE | ||
|---|---|---|---|
| CAS Number | 147221-93-0 | Molecular Weight | 552.667 |
| Density | / | Boiling Point | 732ºC at 760mmHg |
| Molecular Formula | C23H32N6O6S2 | Melting Point | 118-120ºC |
| MSDS | ChineseUSA | Flash Point | 396.5ºC |
Names
| Name | delavirdine mesylate |
|---|---|
| Synonym | More Synonyms |
DELAVIRDINE MESYLATE BiologicalActivity
| Description | Delavirdine mesylate is a potent non-nucleoside HIV-1 reverse transcriptase inhibitor (NNRTI) of HIV-1. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>HIVSignaling Pathways >>Anti-infection >>Reverse TranscriptaseResearch Areas >>Infection |
| References | [1]. Dueweke TJ, et al. U-90152, a potent inhibitor of human immunodeficiency virus type 1 replication. Antimicrob Agents Chemother. 1993 May;37(5):1127-31. [2]. Voorman RL, et al. Interaction of delavirdine with human liver microsomal cytochrome P450: inhibition of CYP2C9, CYP2C19, and CYP2D6. Drug Metab Dispos. 2001 Jan;29(1):41-7. [3]. Shelton MJ, et al. Pharmacokinetics of ritonavir and delavirdine in human immunodeficiency virus-infected patients. Antimicrob Agents Chemother. 2003 May;47(5):1694-9. |
Chemical & Physical Properties
| Boiling Point | 732ºC at 760mmHg |
|---|---|
| Melting Point | 118-120ºC |
| Molecular Formula | C23H32N6O6S2 |
| Molecular Weight | 552.667 |
| Flash Point | 396.5ºC |
| Exact Mass | 552.182495 |
| PSA | 181.56000 |
| LogP | 4.53160 |
| Vapour Pressure | 2.74E-21mmHg at 25°C |
| InChIKey | MEPNHSOMXMALDZ-UHFFFAOYSA-N |
| SMILES | CC(C)Nc1cccnc1N1CCN(C(=O)c2cc3cc(NS(C)(=O)=O)ccc3[nH]2)CC1.CS(=O)(=O)O |
| Storage condition | 2-8℃ |
Safety Information
| RIDADR | NONH for all modes of transport |
|---|
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Synonyms
| DELAVIRDINE, MESYLATE |
| N-{2-[(4-{3-[(1-methylethyl)amino]pyridin-2-yl}piperazin-1-yl)carbonyl]-1H-indol-5-yl}methanesulfonamide methanesulfonate |
| N-[2-({4-[3-(Isopropylamino)pyridin-2-yl]piperazin-1-yl}carbonyl)-1H-indol-5-yl]methanesulfonamide methanesulfonate (1:1) |
| Methanesulfonamide, N-[2-[[4-[3-[(1-methylethyl)amino]-2-pyridinyl]-1-piperazinyl]carbonyl]-1H-indol-5-yl]-, methanesulfonate (1:1) |
| 1-(3-(Isopropylamino)-2-pyridyl)-4-((5-methanesulfonamidoindol-2-yl)carbonyl)piperazine monomethanesulfonate |
| acide méthanesulfonique - N-{2-[(4-{3-[(1-méthyléthyl)amino]pyridin-2-yl}pipérazin-1-yl)carbonyl]-1H-indol-5-yl}méthanesulfonamide (1:1) |
| delavirdine mesilate [INN_en] |
| piperazine, 1-[3-[(1-methylethyl)amino]-2-pyridinyl]-4-[[5-[(methylsulfonyl)amino]-1H-indol-2-yl]carbonyl]-, methanesulfonate (1:1) |
| N-[2-({4-[3-(Isopropylamino)-2-pyridinyl]-1-piperazinyl}carbonyl)-1H-indol-5-yl]methanesulfonamide methanesulfonate (1:1) |
| DELAVIRDINE MESYLATE |
| Piperazine, 1-(3-((1-methylethyl)amino)-2-pyridinyl)-4-((5-((methylsulfonyl)amino)-1H-indol-2-yl)carbonyl)-, monomethanesulfonate |
| Delavirdine monomethanesulfonate |
| Methansulfonsäure--N-{2-[(4-{3-[(1-methylethyl)amino]pyridin-2-yl}piperazin-1-yl)carbonyl]-1H-indol-5-yl}methansulfonamid(1:1) |
| N-[2-({4-[3-(propan-2-ylamino)pyridin-2-yl]piperazin-1-yl}carbonyl)-1H-indol-5-yl]methanesulfonamide methanesulfonate (1:1) |
| Delavirdine (mesylate) |
