CAS 4294-45-5|DL-Threo-beta-Hydroxyaspartic Acid
| Common Name | DL-Threo-beta-Hydroxyaspartic Acid | ||
|---|---|---|---|
| CAS Number | 4294-45-5 | Molecular Weight | 149.10200 |
| Density | 1.738 g/cm3 | Boiling Point | 368.7ºC at 760 mmHg |
| Molecular Formula | C4H7NO5 | Melting Point | >230ºC dec |
| MSDS | ChineseUSA | Flash Point | 176.8ºC |
Names
| Name | D,L-threo-β-Hydroxy Aspartic Acid |
|---|---|
| Synonym | More Synonyms |
DL-Threo-beta-Hydroxyaspartic Acid BiologicalActivity
| Description | DL-threo-3-Hydroxyaspartic acid is a glutamate uptake inhibitor that can block glutamate transport in cannulated sprague dawley rat[1][2]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. A Klegeris,et al. Regulation of glutamate in cultures of human monocytic THP-1 and astrocytoma U-373 MG cells.J Neuroimmunol.1997 Sep;78(1-2):152-61. [2]. Jessica Darman, et al. Viral-induced spinal motor neuron death is non-cell-autonomous and involves glutamate excitotoxicity.J Neurosci. 2004 Aug 25;24(34):7566-75. |
Chemical & Physical Properties
| Density | 1.738 g/cm3 |
|---|---|
| Boiling Point | 368.7ºC at 760 mmHg |
| Melting Point | >230ºC dec |
| Molecular Formula | C4H7NO5 |
| Molecular Weight | 149.10200 |
| Flash Point | 176.8ºC |
| Exact Mass | 149.03200 |
| PSA | 120.85000 |
| Index of Refraction | 1.583 |
| InChIKey | YYLQUHNPNCGKJQ-JCYAYHJZSA-N |
| SMILES | NC(C(=O)O)C(O)C(=O)O |
| Storage condition | 20°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| HS Code | 2922509090 |
Customs
| HS Code | 2922509090 |
|---|---|
| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles30
More Articles| The SLC1 high-affinity glutamate and neutral amino acid transporter family. Mol. Aspects Med. 34(2-3) , 108-20, (2013) Glutamate transporters play important roles in the termination of excitatory neurotransmission and in providing cells throughout the body with glutamate for metabolic purposes. The high-affinity gluta... | |
| A concise, asymmetric synthesis of (2R,3R)-3-hydroxyaspartic acid. Amino Acids 35(2) , 507-10, (2008) 3-Hydroxyaspartic acid and its derivatives are found both in the free form and as peptide constituents in various microorganisms and fungi. Considering the biological importance of this amino acid and... | |
| Insights into the mechanism of Pseudomonas dacunhae aspartate beta-decarboxylase from rapid-scanning stopped-flow kinetics. Biochemistry 49 , 5066-73, (2010) The mechanism of wild-type and R37A mutant Pseudomonas dacunhae aspartate beta-decarboxylase (ABDC) was studied by rapid-scanning stopped-flow spectrophotometry. Mixing wild-type ABDC with 50 mM disod... |
Synonyms
| DL-THREO-β-HYDROXYASPARTIC ACID |
| threo-2-Amino-3-hydroxysuccinic acid |
| DL-Threo-beta-Hydroxyaspartic Acid |
