Introduction：Basic information about CAS 5560-78-1|Teclozan, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Teclozan |
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| CAS Number | 5560-78-1 | Molecular Weight | 502.25900 |
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| Density | 1.294g/cm3 | Boiling Point | 585.8ºC at 760mmHg |
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| Molecular Formula | C20H28Cl4N2O4 | Melting Point | / |
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| MSDS | / | Flash Point | 308.1ºC |
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Names
| Name | 2,2-dichloro-N-[[4-[[(2,2-dichloroacetyl)-(2-ethoxyethyl)amino]methyl]phenyl]methyl]-N-(2-ethoxyethyl)acetamide |
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| Synonym | More Synonyms |
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Teclozan BiologicalActivity
| Description | Teclozan (WIN 13146) is an antiprotozoal agent, class in benzylamine derivatives. Teclozan intervenes in the phospholipid metabolism preventes the formation of arachidonic acid. Teclozan acts in the intestinal lumen being effective in Anti-G. intestinalis. Teclozan can be used for the research of protozoan infections[1][2]. |
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| Related Catalog | Research Areas >>Infection |
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| References | [1]. Gonzales MLM, et al. Antiamoebic drugs for treating amoebic colitis. Cochrane Database Syst Rev. 2019;1(1):CD006085. Published 2019 Jan 9. [2]. Díaz, V. M. M. . Pharmacological Treatment of Giardiasis. In: Rodriguez-Morales, A. J. , editor. Current Topics in Giardiasis [Internet]. London: IntechOpen; 2017. |
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Chemical & Physical Properties
| Density | 1.294g/cm3 |
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| Boiling Point | 585.8ºC at 760mmHg |
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| Molecular Formula | C20H28Cl4N2O4 |
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| Molecular Weight | 502.25900 |
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| Flash Point | 308.1ºC |
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| Exact Mass | 500.08000 |
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| PSA | 59.08000 |
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| LogP | 4.02420 |
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| Index of Refraction | 1.541 |
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| InChIKey | MSJLJWCAEPENBL-UHFFFAOYSA-N |
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| SMILES | CCOCCN(Cc1ccc(CN(CCOCC)C(=O)C(Cl)Cl)cc1)C(=O)C(Cl)Cl |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- AC7720000
- CHEMICAL NAME :
- Acetamide, N,N'-(1,4-phenylenebis(methylene))bis(2,2-dichloro-N- (2-ethoxyethyl)-
- CAS REGISTRY NUMBER :
- 5560-78-1
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C20-H28-Cl4-N2-O4
- MOLECULAR WEIGHT :
- 502.30
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >8 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AJTHAB American Journal of Tropical Medicine and Hygiene. (Allen Press, 1041 New Hampshire St., Lawrence, KS 66044) V.1- 1952- Volume(issue)/page/year: 10,503,1961
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Synonyms
| TECLOZAN |
| EINECS 226-934-0 |
| Teclosan |
| 1,4-Bis-<N-dichloracetyl-N-(2-ethoxy-ethyl)-aminomethyl>-benzol |
| Teclozanum [INN-Latin] |
| Falmonox |
| Teclosine |
| Teclozine |
