CAS 26308-28-1|Ripazepam

Introduction：Basic information about CAS 26308-28-1|Ripazepam, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Ripazepam BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Synonyms

Common Name	Ripazepam
CAS Number	26308-28-1	Molecular Weight	268.31400
Density	1.28g/cm3	Boiling Point	466.6ºC at 760 mmHg
Molecular Formula	C₁₅H₁₆N₄O	Melting Point	/
MSDS	/	Flash Point	236ºC

Names

Name	1-ethyl-3-methyl-8-phenyl-4,6-dihydropyrazolo[4,3-e][1,4]diazepin-5-one
Synonym	More Synonyms

Ripazepam BiologicalActivity

Description	Ripazepam (Cl-683) is a potential antianxiety agent. Ripazepam also is a pyrazolodiazepinone derivative and has anxiolytic effects[1].
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease

Chemical & Physical Properties

Density	1.28g/cm3
Boiling Point	466.6ºC at 760 mmHg
Molecular Formula	C₁₅H₁₆N₄O
Molecular Weight	268.31400
Flash Point	236ºC
Exact Mass	268.13200
PSA	59.28000
LogP	1.57450
Vapour Pressure	6.97E-09mmHg at 25°C
Index of Refraction	1.664
InChIKey	YFHYNLHGFKXAIQ-UHFFFAOYSA-N
SMILES	CCn1nc(C)c2c1C(c1ccccc1)=NCC(=O)N2

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UR0100000

CHEMICAL NAME :: Pyrazolo(4,3-e)(1,4)diazepin-5(1H)-one, 4,6-dihydro-1-ethyl-3-methyl-8-phenyl-

CAS REGISTRY NUMBER :: 26308-28-1

LAST UPDATED :: 199703

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C15-H16-N4-O

MOLECULAR WEIGHT :: 268.35

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 81900 mg/kg/78W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,178,1984 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 66,157,1996 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 66,157,1996 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 66,157,1996

Safety Information

RIDADR	UN 3249
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2933990090

Customs

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

1-ethyl-3-methyl-8-phenyl-4,6-dihydro-1H-pyrazolo[4,3-e][1,4]diazepin-5-one

Ripazepamum [INN-Latin]

RIPAZEPAM

1-Ethyl-1,4,5,6-tetrahydro-3-methyl-8-phenylpyrazolo(4,3-e)(1,4)diazepin-5-on

CI-683

Cl-683

Pyrazapon

Ripazepam [USAN:INN]

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