Introduction：Basic information about CAS 144245-52-3|Fomivirsen, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fomivirsen |
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| CAS Number | 144245-52-3 | Molecular Weight | 6682.40000 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C204H263N63O114P20S20 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Fomivirsen |
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| Synonym | More Synonyms |
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Fomivirsen BiologicalActivity
| Description | Fomivirsen (ISIS-2922 free base) is an antisense 21 mer phosphorothioate oligonucleotide. Fomivirsen is an antiviral agent that is used cytomegalovirus retinitis (CMV) research, incluiding in AIDs. Fomivirsen binds to and degrades the mRNAs encoding CMV immediate-early 2 protein, thus inhibiting virus proliferation[1][2]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>CMV |
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| References | [1]. M D de Smet, et al. Fomivirsen- a phosphorothioate oligonucleotide for the treatment of CMV retinitis. Ocul Immunol Inflamm. 1999 Dec;7(3-4):189-98. [2]. Anna Kilanowska, et al. In vivo and in vitro studies of antisense oligonucleotides – a review. (Review Article) RSC Adv., 2020, 10, 34501-34516. |
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Chemical & Physical Properties
| Molecular Formula | C204H263N63O114P20S20 |
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| Molecular Weight | 6682.40000 |
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| Exact Mass | 6677.59000 |
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| PSA | 3279.10000 |
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| LogP | 15.76190 |
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Synonyms
