Introduction：Basic information about CAS 121305-26-8|H-Leu-Pro-Pro-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | H-Leu-Pro-Pro-OH |
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| CAS Number | 121305-26-8 | Molecular Weight | 325.40300 |
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| Density | 1.247g/cm3 | Boiling Point | 572.6ºC at 760mmHg |
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| Molecular Formula | C16H27N3O4 | Melting Point | / |
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| MSDS | / | Flash Point | 300.1ºC |
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Names
| Name | (2S)-1-[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid |
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| Synonym | More Synonyms |
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H-Leu-Pro-Pro-OH BiologicalActivity
| Description | LPP Tripeptide is a blood pressure lowering tripeptides. LPP Tripeptide can be used for research of hypertension[1]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others |
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| References | [1]. van der Pijl PC, et al. Pharmacokinetics of proline-rich tripeptides in the pig. Peptides. 2008 Dec;29(12):2196-202. |
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Chemical & Physical Properties
| Density | 1.247g/cm3 |
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| Boiling Point | 572.6ºC at 760mmHg |
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| Molecular Formula | C16H27N3O4 |
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| Molecular Weight | 325.40300 |
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| Flash Point | 300.1ºC |
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| Exact Mass | 325.20000 |
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| PSA | 103.94000 |
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| LogP | 1.00250 |
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| Vapour Pressure | 1.33E-14mmHg at 25°C |
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| Index of Refraction | 1.556 |
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| InChIKey | DPURXCQCHSQPAN-AVGNSLFASA-N |
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| SMILES | CC(C)CC(N)C(=O)N1CCCC1C(=O)N1CCCC1C(=O)O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- TW3675000
- CHEMICAL NAME :
- L-Proline, 1-(1-L-leucyl-L-prolyl)-
- CAS REGISTRY NUMBER :
- 121305-26-8
- LAST UPDATED :
- 199506
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C16-H27-N3-O4
- MOLECULAR WEIGHT :
- 325.46
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #90-240027
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Synonyms
| 1-(1-L-Leucyl-L-prolyl)-L-proline |
| L-Proline,1-(1-L-leucyl-L-prolyl) |
