CAS 1180-95-6|Sodium Taurodeoxycholate

Introduction：Basic information about CAS 1180-95-6|Sodium Taurodeoxycholate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Sodium Taurodeoxycholate BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Sodium Taurodeoxycholate
CAS Number	1180-95-6	Molecular Weight	521.685
Density	/	Boiling Point	/
Molecular Formula	C₂₆H₄₄NNaO₆S	Melting Point	168 °C (dec.)(lit.)
MSDS	/	Flash Point	/

Names

Name	Taurodeoxycholic acid sodium salt hydrate
Synonym	More Synonyms

Sodium Taurodeoxycholate BiologicalActivity

Description	Taurodeoxycholate sodium salt is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) inhibits various inflammatory responses[1] [2][3].
Related Catalog	Research Areas >>Inflammation/Immunology
References	[1]. Villavicencio-Queijeiro A, et al. The fully-active and structurally-stable form of the mitochondrial ATP synthase of Polytomella sp. is dimeric. J Bioenerg Biomembr. 2009 Feb;41(1):1-13. [2]. Kispal G,et al. Isolation and characterization of 3-hydroxyacyl coenzyme A dehydrogenase-binding protein from pig heart inner mitochondrial membrane. J Biol Chem. 1986 Oct 25;261(30):14209-13. [3]. Choi HJ, et al. Evaluation of acute and subacute toxicity of sodium taurodeoxycholate in rats. Drug Chem Toxicol. 2019 Jun 19:1-9.

Description

Taurodeoxycholate sodium salt is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) inhibits various inflammatory responses[1] [2][3].

Related Catalog

Research Areas >>Inflammation/Immunology

References

[1]. Villavicencio-Queijeiro A, et al. The fully-active and structurally-stable form of the mitochondrial ATP synthase of Polytomella sp. is dimeric. J Bioenerg Biomembr. 2009 Feb;41(1):1-13.

[2]. Kispal G,et al. Isolation and characterization of 3-hydroxyacyl coenzyme A dehydrogenase-binding protein from pig heart inner mitochondrial membrane. J Biol Chem. 1986 Oct 25;261(30):14209-13.

[3]. Choi HJ, et al. Evaluation of acute and subacute toxicity of sodium taurodeoxycholate in rats. Drug Chem Toxicol. 2019 Jun 19:1-9.

Chemical & Physical Properties

Melting Point	168 °C (dec.)(lit.)
Molecular Formula	C₂₆H₄₄NNaO₆S
Molecular Weight	521.685
Exact Mass	521.278687
PSA	135.14000
LogP	4.52640
InChIKey	YXHRQQJFKOHLAP-UHFFFAOYSA-M
SMILES	CC(CCC(=O)NCCS(=O)(=O)[O-])C1CCC2C3CCC4CC(O)CCC4(C)C3CC(O)C12C.[Na+]
Storage condition	-20℃
Water Solubility	soluble

Safety Information

Hazard Codes	Xi: Irritant;
Risk Phrases	R37
WGK Germany	3

Synonyms

MFCD00003671

Ethanesulfonic acid, 2-[[(3α,5β,12α,20R)-3,12-dihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1)

Sodium 2-(((3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl)amino)ethane-1-sulphonate

EINECS 214-652-0

Sodium 2-{[(3α,5β,12α,20R)-3,12-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonate

Taurodeoxycholate sodium salt

Sodium Taurodeoxycholate

Taurodeoxycholic acid sodiuM salt

Sodium taurodeoxycholate hydrate

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