Introduction：Basic information about CAS 26973-24-0|CTZ, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | CTZ |
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| CAS Number | 26973-24-0 | Molecular Weight | 440.481 |
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| Density | 2.1±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C13H12N8O4S3 | Melting Point | 155ºC (dec.) |
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| MSDS | / | Flash Point | / |
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Names
| Name | (6R,7R)-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-3-(1,3,4-thiadiazol-2-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
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| Synonym | More Synonyms |
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CTZ BiologicalActivity
| Description | Ceftezole (CTZ) is a broad-spectrum cephem antibiotic against many species of gram-positive and gram-negative bacteria. Ceftezole (CTZ) is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity[1][2]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| In Vitro | Ceftezole is a broad-spectrum antibiotic, active in vitro against many species of gram-positive and gram-negative bacteria except, Serratia marcescens and Proteus vulgaris[1]. |
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| References | [1]. Lee DS, et al. Ceftezole, a cephem antibiotic, is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity. Int J Mol Med. 2007 Sep;20(3):379-83. [2]. Harada Y, et al. Ceftezole, a new cephalosporin C derivative II. Distribution and excretion in parenteral administration. J Antibiot (Tokyo). 1976 Oct;29(10):1071-82. |
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Chemical & Physical Properties
| Density | 2.1±0.1 g/cm3 |
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| Melting Point | 155ºC (dec.) |
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| Molecular Formula | C13H12N8O4S3 |
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| Molecular Weight | 440.481 |
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| Exact Mass | 440.014374 |
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| PSA | 234.93000 |
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| LogP | 0.87 |
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| Index of Refraction | 2.003 |
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| InChIKey | DZMVCVMFETWNIU-LDYMZIIASA-N |
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| SMILES | O=C(Cn1cnnn1)NC1C(=O)N2C(C(=O)O)=C(CSc3nncs3)CSC12 |
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| Storage condition | -20℃ |
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Safety Information
| Hazard Codes | T+,N |
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| Risk Phrases | 21/22-26-50/53 |
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| Safety Phrases | 28-36/37-45-61 |
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| HS Code | 3003201400 |
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Customs
Synonyms
| Falomesin |
| Celoslin |
| (6R)-8-oxo-7t-(2-tetrazol-1-yl-acetylamino)-3-[1,3,4]thiadiazol-2-ylsulfanylmethyl-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| 7-(1H-Tetrazol-1-yl)acetamido-3-(1,3,4-thiadiazol-2-ylthio)methylceph-3-em-4-carboxylic Acid |
| Ceftezol |
| 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 8-oxo-7-[[2-(1H-tetrazol-1-yl)acetyl]amino]-3-[(1,3,4-thiadiazol-2-ylthio)methyl]-, (6R,7R)- |
| Ceftezole (INN) |
| CG B3Q |
| CTZ |
| MFCD00274176 |
| Demethylcefazolin |
| (6R,7R)-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-3-[(1,3,4-thiadiazol-2-ylthio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-3-[(1,3,4-thiadiazol-2-ylthio)methyl]-, (6R,7R)- |
| (6R,7R)-8-Oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-3-[(1,3,4-thiadiazol-2-ylsulfanyl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| Ceftezole |
| Ceftezolo |
| CG-B 3 Q |
| Ceftezolum |
